ID   D6EB53_9ACTN            Unreviewed;       697 AA.
AC   D6EB53;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   24-JAN-2024, entry version 69.
DE   SubName: Full=Diguanylate cyclase (GGDEF) domain {ECO:0000313|EMBL:CBL04950.1};
GN   ORFNames=GPA_30580 {ECO:0000313|EMBL:CBL04950.1};
OS   Gordonibacter pamelaeae 7-10-1-b.
OC   Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC   Gordonibacter.
OX   NCBI_TaxID=657308 {ECO:0000313|EMBL:CBL04950.1, ECO:0000313|Proteomes:UP000008805};
RN   [1] {ECO:0000313|EMBL:CBL04950.1, ECO:0000313|Proteomes:UP000008805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=7-10-1-b {ECO:0000313|Proteomes:UP000008805};
RG   metaHIT consortium -- http://www.metahit.eu/;
RA   Pajon A., Turner K., Parkhill J., Timmis K., Oxley A., Wurdemann D.;
RT   "The genome sequence of Gordonibacter pamelaeae 7-10-1-bT.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBL04950.1, ECO:0000313|Proteomes:UP000008805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=7-10-1-b {ECO:0000313|Proteomes:UP000008805};
RA   Pajon A.;
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FP929047; CBL04950.1; -; Genomic_DNA.
DR   RefSeq; WP_015540294.1; NC_021021.1.
DR   AlphaFoldDB; D6EB53; -.
DR   GeneID; 78359687; -.
DR   KEGG; gpa:GPA_30580; -.
DR   PATRIC; fig|657308.3.peg.2508; -.
DR   HOGENOM; CLU_000445_92_10_11; -.
DR   BioCyc; GPAM657308:GPA_RS14170-MONOMER; -.
DR   Proteomes; UP000008805; Chromosome.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR   PANTHER; PTHR45228:SF5; CYCLIC DI-GMP PHOSPHODIESTERASE VC_1348-RELATED; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00471; HDc; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008805}.
FT   DOMAIN          6..123
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          143..351
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   DOMAIN          543..669
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   MOD_RES         56
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   697 AA;  78682 MW;  DB40EAEBF060DF99 CRC64;
     MRKRSQILIV DDSELNRSML ADILYKEYDV LEAENGREAI AMLQEHEHEI SLMLLDIVMP
     EMDGFEVLAV MGKNKWLESI PVIIISAESA STYIDSAYDL GATEYISRPF DPKAVQRRVG
     NTVLLYSKQK MLENMVTNQM LDKEKSNLIM VEVLSHIVEF RNGESGMHVL NIRSITKMLL
     AQLCRISDQY SAIQPRIPLI ANASALHDIG KISISESILN KPGKLTPEEW LIMKTHSEAG
     ANILESTRYY PHEELVSVAR DICRWHHERY DGKGYPDGLV GDDIPIEAQV VALADVYDAL
     THKRVYKEAL PHEVSMRMIF DGECGAFNPL LLQCLADIGP QLEKELKLKS LGHASKDEMI
     DATRSMMQSG NVSNRTLALL EQERIKYQFF ADLSREIQFE YTAHTDTLML SEWGASQLGL
     PSFIENPNGN PELLRVMVRR DMESLRNLIL SASPKDPKVS GHYLLNVNGT RRWHKFLARP
     LWLGNDADIF TGFIGKCIDV HDERLKMDRL IEQANTDALT GLYHRKAARK VVQEALDEAE
     SGMCFTLMLF DLDFFKHAND HYGHLFGDEL LQETARRMLG AVRDVDITAR IGGDEFLIFI
     ESPLDSTPAV ERIFSSLRCT CKGHPITVSM GVARAPQDGM QFDELFHCAD RALYAAKQRG
     RNCYCLYDDS MAGQLSVLSE IPSEEAGEQS PDQACGQ
//