ID D6EG95_STRLI Unreviewed; 1085 AA.
AC D6EG95;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=SSPG_07232 {ECO:0000313|EMBL:EFD71592.2};
OS Streptomyces lividans TK24.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=457428 {ECO:0000313|EMBL:EFD71592.2};
RN [1] {ECO:0000313|EMBL:EFD71592.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TK24 {ECO:0000313|EMBL:EFD71592.2};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Kodira C.D., Zeng Q.,
RA Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I.,
RA Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA Sykes S.N., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Galagan J., Nusbaum C., Birren B.;
RT "The genome sequence of Streptomyces lividans strain TK24.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
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DR EMBL; GG657756; EFD71592.2; -; Genomic_DNA.
DR RefSeq; WP_003978497.1; NZ_GG657756.1.
DR AlphaFoldDB; D6EG95; -.
DR HOGENOM; CLU_002926_1_1_11; -.
DR Proteomes; UP000002769; Unassembled WGS sequence.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR016007; Alpha_rhamnosid.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307:SF11; ALPHA-L-RHAMNOSIDASE; 1.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR PIRSF; PIRSF010631; A-rhamnsds; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 360..537
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 548..643
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 651..976
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 979..1050
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 1085 AA; 117303 MW; ADE272F1772D581B CRC64;
MPRTNPPVRH RTAAALAGVT AFVTLLAGAV TADAATTGTI TPTALRTQHL TEALGIDDTT
PDLNWQTTAG APNTRQAAYR VQAATSLQRL RASRPDLWDS GKVESSVPGT TYAGKDPGSR
AKVYWRVMLW SGKGKRHSGW STTAVFETGL TRQSDWDAQW ITHPDWRLSD RTVEPVVVHL
PRTTARYVRL DVTRLGLPLA ESFPDRTWRL QLGEIDVRDS TTATTGLARG AAVTASESNT
VRKSWEPALA VDGLPNSALQ TAAGYASAAH TGPDVSGAPI TLTLDLKSVK TFDEVALYPR
ADVLTDDGRI PGLPVDYTVS AADSADGPAT RLAAVSGQRQ PTPYLPAGLP LLTDDFTLPK
RVRSARLYIA GLGVYDATVN GEPVGDAVLE PANTDFAERV QYATYDVTDR LRTGANTLGV
ALGNGMSNVV STADRYRKLY GNLSDPKLIA RLEVTLADGR VRTITSGDDW RTTLGPTTAS
NWYGGEDYDA RREIPRWDEP AGDRRGWRHA VAVAGPGTAD RPALLSARET EPIRVVETLK
GKEVDGAEGS RVFDLGRNIA GWPEITVRAP QGTAIRVYPA ESLKDGHAFQ SISNVGAPLW
DSYTTAGGRH AESWHPRFSY HGFRYLELRG VPENATVSVR GHVLRTDNAS AGDFTSSDPL
INGIHSLIRR SIEGNMMSVL TDCPSREKLG WLEQNQLVFP ALAGNYDMRA YLRKIVRDMA
DAQTPDGLVP STVPEYTSLP GAYRNDSNWG GAFVLVPWQL YLTYGDRQTL ETYYPDMRRY
AAFLEAQAAD GILDYGLGDW FTPDRTFPRA VAGTYGYWRV VDTLGRIASL LGDTAAADEY
RRKAAASVEA LTAKYYDATT GTFGGGGHGA EALALDMGAY PQGERDRLLS HFTDAIKDAG
NHLVLGEISL PAAFRVLSAA DRDDEVHAIA TQTTSPSYGY QVLAGNTTLG ESWDGGPGQS
QNHFMLGAID SWFTTRVAGI SQTEDSVGYA KLLVDPAVEG DMTSAAGSYR TPYGVARTDW
ERSDDRFRLT VDVPAGSTAE VHVPVAGEHA EAPGSARLLR LTGGEAVYEV GSGHWTFRST
MERGR
//
