ID D6JD89_ECOLX Unreviewed; 304 AA.
AC D6JD89;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Fructokinase {ECO:0000313|EMBL:EFF13718.2};
GN ORFNames=ECEG_01741 {ECO:0000313|EMBL:EFF13718.2};
OS Escherichia coli B354.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=550677 {ECO:0000313|EMBL:EFF13718.2, ECO:0000313|Proteomes:UP000004683};
RN [1] {ECO:0000313|EMBL:EFF13718.2, ECO:0000313|Proteomes:UP000004683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B354 {ECO:0000313|EMBL:EFF13718.2,
RC ECO:0000313|Proteomes:UP000004683};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Feldgarden M., Gordon D.M., Johnson J.R., Johnston B.D., Young S., Zeng Q.,
RA Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Escherichia coli B354.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000256|ARBA:ARBA00010688, ECO:0000256|RuleBase:RU003704}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG749328; EFF13718.2; -; Genomic_DNA.
DR RefSeq; WP_001274887.1; NZ_GG749328.1.
DR AlphaFoldDB; D6JD89; -.
DR GeneID; 75202569; -.
DR Proteomes; UP000004683; Unassembled WGS sequence.
DR GO; GO:0008865; F:fructokinase activity; IEA:UniProt.
DR GO; GO:0006000; P:fructose metabolic process; IEA:UniProt.
DR CDD; cd01167; bac_FRK; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR002139; Ribo/fructo_kinase.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR43085; HEXOKINASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43085:SF1; KETOHEXOKINASE; 1.
DR Pfam; PF00294; PfkB; 1.
DR PRINTS; PR00990; RIBOKINASE.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS00583; PFKB_KINASES_1; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|RuleBase:RU003704, ECO:0000313|EMBL:EFF13718.2};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003704}.
FT DOMAIN 3..298
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 304 AA; 33049 MW; B0359569939B9D97 CRC64;
MSAKVWVLGD AVVDLLPESD GRLLPCPGGA PANVAVGIAR LGGTSGFIGR VGDDPFGALM
QRTLLTEGVD ITYLKQDEWH RTSTVLVDLN DQGERSFTFM VRPSADLFLE TTDLPCWRHG
EWLHLCSIAL SAEPSRTSAF TAMTAIRHAG GFVSFDPNIR EDLWQDEHLL RLCLRQALQL
ADVVKLSEEE WRLISGKTQN DRDICALAKE YEIAMLLVTK GAEGVVVCYR GQVHHFAGMS
VNCVDSTGAG DAFVAGLLTG LSSTGLSTDE REMRRIIDLA QRCGALAVTA KGAMTALPCR
QELE
//
