ID D6K5E1_9ACTN Unreviewed; 360 AA.
AC D6K5E1;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Xylose repressor {ECO:0000313|EMBL:EFF89786.2};
GN ORFNames=SSTG_00104 {ECO:0000313|EMBL:EFF89786.2};
OS Streptomyces sp. e14.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=645465 {ECO:0000313|EMBL:EFF89786.2, ECO:0000313|Proteomes:UP000004704};
RN [1] {ECO:0000313|EMBL:EFF89786.2, ECO:0000313|Proteomes:UP000004704}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=e14 {ECO:0000313|Proteomes:UP000004704};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Streptomyces sp. strain e14.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
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DR EMBL; GG753626; EFF89786.2; -; Genomic_DNA.
DR RefSeq; WP_009187370.1; NZ_GG753626.1.
DR AlphaFoldDB; D6K5E1; -.
DR STRING; 645465.SSTG_00104; -.
DR eggNOG; COG1846; Bacteria.
DR eggNOG; COG1940; Bacteria.
DR OrthoDB; 3189808at2; -.
DR Proteomes; UP000004704; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000835; HTH_MarR-typ.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF12802; MarR_2; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000004704}.
FT DOMAIN 31..81
FT /note="HTH marR-type"
FT /evidence="ECO:0000259|Pfam:PF12802"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 360 AA; 37009 MW; B1371F60BC6A6B6F CRC64;
MSAPLHEHHP AGPRRALPDT QQGMRRRNLA RVMHTVSAEG PLSRAAVASR IGLTRAAVST
LVDELIRSGL LEELGPERPG RVGRPGSALA VSARGPAGVG AEVGVDHLAA CVVDLRGEVR
ARAVRHGTNR GRSPEPVAEE LTALISQVVA EAEAQGLWPA GLAVAVPGLI ARDGRTVVRA
PNLDWHDTDL SALLPDEFGP AVDNEANFGA LAELWLGEGT PQDFLHVSAE IGIGAAVVVD
GRLLRGTRGF AGELGHVPVE PEGPACPCGG RGCLEQYAGE EAVLRAAGLT AGEGRVGLLA
TRAAEGDEAV RRALRDAGRA LGIALTGAVN LLDPEAVVLG AAHSVIRTVL DDPAAAAGRA
//
