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Database: UniProt
Entry: D6K815_9ACTN
LinkDB: D6K815_9ACTN
Original site: D6K815_9ACTN 
ID   D6K815_9ACTN            Unreviewed;       767 AA.
AC   D6K815;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-SEP-2017, entry version 41.
DE   RecName: Full=Protein translocase subunit SecD {ECO:0000256|HAMAP-Rule:MF_01463};
GN   Name=secD {ECO:0000256|HAMAP-Rule:MF_01463};
GN   ORFNames=SSTG_02441 {ECO:0000313|EMBL:EFF92122.2};
OS   Streptomyces sp. e14.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=645465 {ECO:0000313|EMBL:EFF92122.2, ECO:0000313|Proteomes:UP000004704};
RN   [1] {ECO:0000313|EMBL:EFF92122.2, ECO:0000313|Proteomes:UP000004704}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=e14 {ECO:0000313|Proteomes:UP000004704};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA   Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA   Sykes S.N., Thomson T., Walk T., White J., Yandava C., Straight P.,
RA   Clardy J., Hung D., Kolter R., Mekalanos J., Walker S., Walsh C.T.,
RA   Wieland-Brown L.C., Haas B., Nusbaum C., Birren B.;
RT   "The genome sequence of Streptomyces sp. strain e14.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the Sec protein translocase complex. Interacts
CC       with the SecYEG preprotein conducting channel. SecDF uses the
CC       proton motive force (PMF) to complete protein translocation after
CC       the ATP-dependent function of SecA. {ECO:0000256|HAMAP-
CC       Rule:MF_01463, ECO:0000256|SAAS:SAAS00541769}.
CC   -!- SUBUNIT: Forms a complex with SecF. Part of the essential Sec
CC       protein translocation apparatus which comprises SecA, SecYEG and
CC       auxiliary proteins SecDF. Other proteins may also be involved.
CC       {ECO:0000256|HAMAP-Rule:MF_01463}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01463}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_01463}.
CC   -!- SIMILARITY: Belongs to the SecD/SecF family. SecD subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_01463}.
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DR   EMBL; GG753626; EFF92122.2; -; Genomic_DNA.
DR   STRING; 645465.SSTG_02441; -.
DR   EnsemblBacteria; EFF92122; EFF92122; SSTG_02441.
DR   eggNOG; ENOG4107RSV; Bacteria.
DR   eggNOG; COG0342; LUCA.
DR   OrthoDB; POG091H02C5; -.
DR   Proteomes; UP000004704; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005622; C:intracellular; IEA:GOC.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   GO; GO:0043952; P:protein transport by the Sec complex; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01463_B; SecD_B; 1.
DR   InterPro; IPR005791; SecD.
DR   InterPro; IPR022813; SecD/SecF_arch_bac.
DR   InterPro; IPR022645; SecD/SecF_bac.
DR   InterPro; IPR022646; SecD/SecF_CS.
DR   Pfam; PF07549; Sec_GG; 2.
DR   Pfam; PF02355; SecD_SecF; 1.
DR   TIGRFAMs; TIGR00916; 2A0604s01; 1.
DR   TIGRFAMs; TIGR01129; secD; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01463,
KW   ECO:0000256|SAAS:SAAS00425060};
KW   Complete proteome {ECO:0000313|Proteomes:UP000004704};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01463,
KW   ECO:0000256|SAAS:SAAS00284057};
KW   Protein transport {ECO:0000256|HAMAP-Rule:MF_01463,
KW   ECO:0000256|SAAS:SAAS00425133};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004704};
KW   Translocation {ECO:0000256|HAMAP-Rule:MF_01463,
KW   ECO:0000256|SAAS:SAAS00425069};
KW   Transmembrane {ECO:0000256|HAMAP-Rule:MF_01463,
KW   ECO:0000256|SAAS:SAAS00425065};
KW   Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_01463,
KW   ECO:0000256|SAAS:SAAS00425143};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_01463,
KW   ECO:0000256|SAAS:SAAS00425109}.
FT   TRANSMEM    284    304       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01463}.
FT   TRANSMEM    309    331       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01463}.
FT   TRANSMEM    337    356       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01463}.
FT   TRANSMEM    377    404       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01463}.
FT   TRANSMEM    410    434       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01463}.
FT   TRANSMEM    476    496       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01463}.
SQ   SEQUENCE   767 AA;  80020 MW;  C54D7E9EE23709CC CRC64;
     MIRSARVRAL FALAVIAVSL YIAATVPVRL GLDLRGGTQI VLETRSTPTA EADRAATDRT
     LEVLRGRVDA LGVAEPTLVR SGAHRIIVEL PGVQDPKKGG RGARPHRAAH RPPGPRPGPA
     PRTGRRRRRE STKAGSGEQV LPDESVQRLR LAATAMTGED VKGADARFDP ETGAGWHVTV
     DFDRAGRERW AKLTGEAACR PAGDPARRVA IVLDGRIISA PQVDPSVACG TGIAGGSTQI
     TGSFDDAEAR ELALLINGGA LPVPVETVEQ HTVGPTLGAR AITASAWAAV IGTALTALFI
     IVVYRLMGVL AAVALLAYGL ISYAALAALG ATLTLPGLAG FVLAIGMAVD ANVLVFERAR
     EEYAARVRPT GRSALTAGFR NAFSAIADSN VTTLIAAGLL FFLASGPVRG FGVTLGIGVV
     ASMISALVVT RVLADFAVSR AWVHRRPGVT GLATAGRVRA ALARRELRPM RRPRRWLAAS
     AVALVLAGSG IAVRGLDLGL EFTGGRMLQY DTGRAVDPER ARTALADAGF PGAVVQTAGE
     TGLTVRTGEL TDARADAVTR TVGALGGGAE KVRDELIGPS LGEELRRGAL ISLGVALGGA
     AAVSRGAVPL AVRDGGGRRA RARRGDPRRR VRVAGQAGGR GVPRRAADGD RLLGQRLGRR
     LRPRPGTGPA GPRGAAGRRH RPGHPPDPAA HGEHRDGRGP HPRLPGRPRR RLPDRLRPRP
     AHRPGGRHVL VGLHRLADRR RTRPPAARPT RGGTAAGRAP ARTGQAA
//
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