ID D6KAX9_9ACTN Unreviewed; 642 AA.
AC D6KAX9;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=Ferredoxin oxidoreductase, alpha subunit {ECO:0000313|EMBL:EFF92510.2};
GN ORFNames=SSTG_02829 {ECO:0000313|EMBL:EFF92510.2};
OS Streptomyces sp. e14.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=645465 {ECO:0000313|EMBL:EFF92510.2, ECO:0000313|Proteomes:UP000004704};
RN [1] {ECO:0000313|EMBL:EFF92510.2, ECO:0000313|Proteomes:UP000004704}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=e14 {ECO:0000313|Proteomes:UP000004704};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Streptomyces sp. strain e14.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG753626; EFF92510.2; -; Genomic_DNA.
DR RefSeq; WP_009190068.1; NZ_GG753626.1.
DR AlphaFoldDB; D6KAX9; -.
DR STRING; 645465.SSTG_02829; -.
DR eggNOG; COG0674; Bacteria.
DR eggNOG; COG1014; Bacteria.
DR OrthoDB; 9794954at2; -.
DR Proteomes; UP000004704; Unassembled WGS sequence.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR InterPro; IPR022367; 2-oxoacid/accept_OxRdtase_asu.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR NCBIfam; TIGR03710; OAFO_sf; 1.
DR PANTHER; PTHR32154:SF20; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORA; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01558; POR; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000004704}.
FT DOMAIN 44..231
FT /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01558"
FT DOMAIN 286..499
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 541..624
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 642 AA; 68961 MW; DDDDE38B160D259E CRC64;
MTSQVSSPTE QADGAVLGEQ RGAAGTKDVR RLERVIIRFA GDSGDGMQLT GDRFTSETAS
FGNDLSTLPN FPAEIRAPAG TLPGVSSFQL HFADHDILTP GDAPNVLVAM NPAALKANIG
DLPRGAEIIV NTDEFTKRAM QKVGYAASPL EDGSLDGYQL HPVPLTTLTV EALKEFDLSR
KEAERSKNMF ALGLLSWMYH RPTEGTEKFL RTKFAKKPDI AAANIAAFRA GWNFGETTED
FAVSYEVAPA AQAFPVGTYR NISGNLALAY GLVAASRQAD LPLYLGSYPI TPASDILHEL
SKHKNFGVRT FQAEDEIAGI GAALGAAFGG ALAVTTTSGP GVALKSETIG LAVSLELPLL
VVDIQRGGPS TGLPTKTEQA DLLQAMYGRN GEAPVPVVAP RTPADCFDAA LEAARIALAY
RTPVFLLSDG YLANGSEPWR IPELDELPDL RVRFATGPNH TLADGTEVFW PYKRDARTLA
RPWAIPGTPG LEHRIGGIEK QDGTGNISYD PANHDFMVRT RQAKVDGIDV PDIEVDDPDR
ARTLVLGWGS TYGPITAAVR RLRTAGEAIA QAHLRHLNPF PKNLGTVLER YDKVVIPEMN
LGQLATLVRA KYLVDAHSYN QVNGMPFKAE QLATALKEAI DG
//
