ID   D6KGN0_9ACTN            Unreviewed;       319 AA.
AC   D6KGN0;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Aldo/keto reductase family oxidoreductase {ECO:0000313|EMBL:EFF88276.2};
GN   ORFNames=SSTG_06106 {ECO:0000313|EMBL:EFF88276.2};
OS   Streptomyces sp. e14.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=645465 {ECO:0000313|EMBL:EFF88276.2, ECO:0000313|Proteomes:UP000004704};
RN   [1] {ECO:0000313|EMBL:EFF88276.2, ECO:0000313|Proteomes:UP000004704}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=e14 {ECO:0000313|Proteomes:UP000004704};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA   Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA   Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA   Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA   Haas B., Nusbaum C., Birren B.;
RT   "The genome sequence of Streptomyces sp. strain e14.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the shaker potassium channel beta subunit
CC       family. {ECO:0000256|ARBA:ARBA00006515}.
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DR   EMBL; GG753631; EFF88276.2; -; Genomic_DNA.
DR   AlphaFoldDB; D6KGN0; -.
DR   STRING; 645465.SSTG_06106; -.
DR   eggNOG; COG0667; Bacteria.
DR   Proteomes; UP000004704; Unassembled WGS sequence.
DR   Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR   InterPro; IPR005399; K_chnl_volt-dep_bsu_KCNAB-rel.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43150; HYPERKINETIC, ISOFORM M; 1.
DR   PANTHER; PTHR43150:SF4; L-GLYCERALDEHYDE 3-PHOSPHATE REDUCTASE; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004704}.
FT   DOMAIN          16..317
FT                   /note="NADP-dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00248"
SQ   SEQUENCE   319 AA;  34950 MW;  FAB3C5930D7C562E CRC64;
     MPYRRTGRSG LKLPALSLGL WHNFGPDRPA ETQRAILRRA FDLGVTHFDL ANNYGPPPGA
     AESALGEALR ADFAPYRDEL VISTKAGYLM WPGPYGEWGS RKYLLSSLDQ SLKRLGLEYV
     DVFYSHRFDP DTPLEETMGA LHSAVQQGKA LYVGVSNYSA EQTREAARIL GELGTPLLIH
     QPRYSMLDRR PEDEGLLDAL DELEIGSIAY SPLEQGLLTA RYLDGIPEDS RAASDSPFLN
     SDAVTGELVE RLRALNKLAE SRGQSLAQLA LAWVLRGGRV TSALVGASSP RQLEDSVAAI
     GNLDFDAEEL ARIDAIVRP
//