ID D6M4D8_STRSH Unreviewed; 714 AA.
AC D6M4D8;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Dipeptidyl peptidase IV {ECO:0000313|EMBL:EFG65609.2};
GN ORFNames=SSBG_06438 {ECO:0000313|EMBL:EFG65609.2};
OS Streptomyces sp. (strain SPB074).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=465543 {ECO:0000313|EMBL:EFG65609.2, ECO:0000313|Proteomes:UP000002779};
RN [1] {ECO:0000313|Proteomes:UP000002779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPB074 {ECO:0000313|Proteomes:UP000002779};
RG The Broad Institute Genome Sequencing Platform;
RA Fischbach M., Ward D., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA Hepburn T., Sykes S., Alvarado L., Kodira C.D., Straight P., Clardy J.,
RA Hung D., Kolter R., Mekalanos J., Walker S., Walsh C.T., Lander E.,
RA Galagan J., Nusbaum C., Birren B.;
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EFG65609.2, ECO:0000313|Proteomes:UP000002779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPB074 {ECO:0000313|Proteomes:UP000002779};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Streptomyces sp. strain SPB74.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG770539; EFG65609.2; -; Genomic_DNA.
DR RefSeq; WP_008749195.1; NZ_GG770539.1.
DR AlphaFoldDB; D6M4D8; -.
DR ESTHER; 9acto-d6m4d8; DPP4N_Peptidase_S9.
DR Proteomes; UP000002779; Unassembled WGS sequence.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF193; DIPEPTIDYL PEPTIDASE 9; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
FT DOMAIN 113..311
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 501..699
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT REGION 97..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 714 AA; 75021 MW; AE57233FAB10F36C CRC64;
MHPTPPTRAQ LRAFPDQFAR SARFSRGRPH SFTVSDDGRR VLFLRSVSGT RAPLRLWLYE
SGAGTERPLT GPGVSAYTAD APARHVVVAL PGGGLATLDT DTPAPPRPLT GTRGVEAPRL
APGGARFAFV RHGALHVAPW PGGDDRVRCL LAPEGPEVAY GLPDPVARGE IRREEAYWWA
PGGDALLVAR TDESGVARRW LGDPAHPERP PRVLRDPAAG TANAVTSLHL VAVDGGGARR
VALPARAGAG HPEGAWCAPE FEYLVAAGWD AHGPWASVQS RDQRTVRTLA LDPADGSART
LAEEHDPYWV ALLPGAPLRT AAGTLVTARV LADGTRGLAA GTATTPEGFE VREVLGARGE
EILLRAGTDP AEVHVWAWTP GTAPERLSGP GPGVYEGATG GPTLVIDGLG PRGRTVRVTT
GGASGTGAVT APRTGVLRSL EETPLVLPRP RYLRLGSRAL RGALFLPSRH TPGTRLPVLL
SPYGGYGLGL VVRARTWWAA VAQWFAEHGF AVLVTDGRGT PGRGAPWEYA IHGDRLTAPL
ADQADALRAA AEAYPDLDPG RVGIRGWSYG GYLAAAAVLR HPETFHAAVA GAAPADRSLY
RTHWEERFLG DPAVLPEGYR ASSLLDDAPR LRRPLLLVHG LADENVSPAH MLRLSAALLA
AGRPHEVLPL SGAGHGVAGT PLAAALLRHE VRWLGAALGV AVDAPGGSRP APEA
//
