ID D6M4X1_STRSH Unreviewed; 402 AA.
AC D6M4X1;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Two-component sensor kinase {ECO:0000313|EMBL:EFG64622.2};
DE Flags: Fragment;
GN ORFNames=SSBG_05412 {ECO:0000313|EMBL:EFG64622.2};
OS Streptomyces sp. (strain SPB074).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=465543 {ECO:0000313|EMBL:EFG64622.2, ECO:0000313|Proteomes:UP000002779};
RN [1] {ECO:0000313|Proteomes:UP000002779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPB074 {ECO:0000313|Proteomes:UP000002779};
RG The Broad Institute Genome Sequencing Platform;
RA Fischbach M., Ward D., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA Hepburn T., Sykes S., Alvarado L., Kodira C.D., Straight P., Clardy J.,
RA Hung D., Kolter R., Mekalanos J., Walker S., Walsh C.T., Lander E.,
RA Galagan J., Nusbaum C., Birren B.;
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EFG64622.2, ECO:0000313|Proteomes:UP000002779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPB074 {ECO:0000313|Proteomes:UP000002779};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Streptomyces sp. strain SPB74.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG770539; EFG64622.2; -; Genomic_DNA.
DR AlphaFoldDB; D6M4X1; -.
DR Proteomes; UP000002779; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR Pfam; PF17203; sCache_3_2; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EFG64622.2}; Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:EFG64622.2};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 58..191
FT /note="Single cache"
FT /evidence="ECO:0000259|Pfam:PF17203"
FT NON_TER 402
FT /evidence="ECO:0000313|EMBL:EFG64622.2"
SQ SEQUENCE 402 AA; 43038 MW; 14771716FABC2D2D CRC64;
MRSRGPAPGA PACALLGHTV PMRLPRPRSL AGQLFAMQVL LVALVVAGCA LFTYVSDRRQ
ARTAAERQVT AAALAIAAAP TVREAVGAPE PTRVLQPYAE KVRREADLTF VTIMSPEGIR
YTHPTPDRIG ERFLGHRAEA LRGRTFSETY RGTLGVSVRV VTPVKDGDRV TGLVSAGIDV
TAISERLRHQ VLLLLVTAAA ALLLGGTGTY VINRRLRRHT HGMNATELAL VHDYHEAALH
AVREGLLMLD GHRAVALLND GARELLGLPP GGYVGRPVAE LGLPRGLTGA LLASEPRVDE
VHLTEERVLV VNTSPVSGGQ RSGTVVTLRD HTELRALMGE LDAERSFGKA LRAQAHEAAN
RLHTVVSLVE LGRPEEAVEF ATAELELAQA LTDRMTGAVG EP
//
