ID D6PKL7_9ZZZZ Unreviewed; 125 AA.
AC D6PKL7;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 13-SEP-2023, entry version 27.
DE RecName: Full=ATP phosphoribosyltransferase {ECO:0000256|ARBA:ARBA00011946};
DE EC=2.4.2.17 {ECO:0000256|ARBA:ARBA00011946};
OS uncultured organism MedDCM-OCT-S08-C1481.
OC unclassified sequences; environmental samples.
OX NCBI_TaxID=743630 {ECO:0000313|EMBL:ADD96268.1};
RN [1] {ECO:0000313|EMBL:ADD96268.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20393571; DOI=10.1038/ismej.2010.44;
RA Ghai R., Martin-Cuadrado A.B., Molto A.G., Heredia I.G., Cabrera R.,
RA Martin J., Verdu M., Deschamps P., Moreira D., Lopez-Garcia P., Mira A.,
RA Rodriguez-Valera F.;
RT "Metagenome of the Mediterranean deep chlorophyll maximum studied by direct
RT and fosmid library 454 pyrosequencing.";
RL ISME J. 4:1154-1166(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-
CC alpha-D-ribose 1-diphosphate + ATP; Xref=Rhea:RHEA:18473,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:58017,
CC ChEBI:CHEBI:73183; EC=2.4.2.17;
CC Evidence={ECO:0000256|ARBA:ARBA00000915};
CC -!- PATHWAY: Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine
CC from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.
CC {ECO:0000256|ARBA:ARBA00004667}.
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DR EMBL; GU943129; ADD96268.1; -; Genomic_DNA.
DR AlphaFoldDB; D6PKL7; -.
DR UniPathway; UPA00031; UER00006.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0003879; F:ATP phosphoribosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR013820; ATP_PRibTrfase_cat.
DR InterPro; IPR001348; ATP_PRibTrfase_HisG.
DR NCBIfam; TIGR00070; hisG; 1.
DR PANTHER; PTHR21403:SF8; ATP PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR21403; ATP PHOSPHORIBOSYLTRANSFERASE ATP-PRTASE; 1.
DR Pfam; PF01634; HisG; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Histidine biosynthesis {ECO:0000256|ARBA:ARBA00023102};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 51..124
FT /note="ATP phosphoribosyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01634"
SQ SEQUENCE 125 AA; 14066 MW; CC9FDC390F5CDF0C CRC64;
MIRLAISKGR ILEQAIEILR RININCKFNP IDSRKLIIPT NMKNLEIIVI KASDVPVYID
SGKVDIGIVG FDTLLEESLG NHYRLLDLQI AKCKLVVAGK PNTAYFNNMK IATKYPNAAK
TILKR
//
