ID   D6PT30_9ROSI            Unreviewed;       380 AA.
AC   D6PT30;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=alcohol dehydrogenase {ECO:0000256|ARBA:ARBA00013190};
DE            EC=1.1.1.1 {ECO:0000256|ARBA:ARBA00013190};
GN   Name=ADH1 {ECO:0000313|EMBL:ADF80914.1};
OS   Vitis vulpina.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=754105 {ECO:0000313|EMBL:ADF80914.1};
RN   [1] {ECO:0000313|EMBL:ADF80914.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Jiang K., Goertzen L.R.;
RT   "Characterization of RPB2 gene and multi-locus phylogenetic analyses in
RT   North American grapevines (Vitis spp.).";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; GU968582; ADF80914.1; -; Genomic_DNA.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08301; alcohol_DH_plants; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR43880:SF40; ALCOHOL DEHYDROGENASE 2; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          37..158
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          206..337
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   380 AA;  41085 MW;  E4EAF681F0560176 CRC64;
     MSGTAGQVIC CKAAVAWEAG KPLVIEEVEV APPQAMEVRL KILYTSLCHT DVYFWEAKGQ
     TPLFPRIFGH EAGGIVESVG EGVTDLKPGD HVLPIFTGEC KDCAHCKSEE SNLCDLLRIN
     TDRGVMIHDG KSRFTIKGKP VYHFLGTSTF SEYTVVHVGC VAKINPLAPL DKVCVLSCGI
     STGLGATLNV AKPTKGSTVA VFGLGAVGLA AAEGARIAGA SRIIGVDLNP KRYEGAKKFG
     VTDFVNPKDH EKSVQEVIVE MTGGGVDRSL ECTGNVNAMI SAFECVHDGW GVAVIVGVPN
     KDDVFKTHPI NLLNERTLKG TFFGNYKPRS DIPAVVEKYM NKELEVEKFI THSVPFSEIN
     KAFEYMLKGE SLRCIIHMEX
//