ID D6RDA0_HUMAN Unreviewed; 95 AA.
AC D6RDA0;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=SKI3 subunit of superkiller complex {ECO:0000313|Ensembl:ENSP00000425403.1};
DE Flags: Fragment;
GN Name=SKIC3 {ECO:0000313|Ensembl:ENSP00000425403.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000425403.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000425403.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15372022; DOI=10.1038/nature02919;
RA Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT "The DNA sequence and comparative analysis of human chromosome 5.";
RL Nature 431:268-274(2004).
RN [2] {ECO:0007829|PubMed:22814378}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-terminal
RT acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
RN [3] {ECO:0000313|Ensembl:ENSP00000425403.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC090071; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; D6RDA0; -.
DR SMR; D6RDA0; -.
DR MassIVE; D6RDA0; -.
DR MaxQB; D6RDA0; -.
DR PeptideAtlas; D6RDA0; -.
DR ProteomicsDB; 14069; -.
DR Antibodypedia; 48952; 30 antibodies from 16 providers.
DR Ensembl; ENST00000513823.5; ENSP00000425403.1; ENSG00000198677.13.
DR UCSC; uc063fmg.1; human.
DR HGNC; HGNC:23639; SKIC3.
DR VEuPathDB; HostDB:ENSG00000198677; -.
DR GeneTree; ENSGT00390000016407; -.
DR HOGENOM; CLU_2378145_0_0_1; -.
DR OMA; CQWELDP; -.
DR ChiTaRS; TTC37; human.
DR Proteomes; UP000005640; Chromosome 5.
DR Bgee; ENSG00000198677; Expressed in calcaneal tendon and 208 other cell types or tissues.
DR ExpressionAtlas; D6RDA0; baseline and differential.
DR GO; GO:0055087; C:Ski complex; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR039226; Ski3/TTC37.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR15704; SUPERKILLER 3 PROTEIN-RELATED; 1.
DR PANTHER; PTHR15704:SF7; TETRATRICOPEPTIDE REPEAT PROTEIN 37; 1.
DR Pfam; PF14559; TPR_19; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:D6RDA0,
KW ECO:0007829|MaxQB:D6RDA0};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 40..73
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT NON_TER 95
FT /evidence="ECO:0000313|Ensembl:ENSP00000425403.1"
SQ SEQUENCE 95 AA; 10825 MW; 4FF1466BB3813EC9 CRC64;
MSSKEVKTAL KSARDAIRNK EYKEALKHCK TVLKQEKNNY NAWVFIGVAA AELEQPDQAQ
SAYKKAAELE PDQLLAWQGL ANLYEKYNHI NAKDD
//
