ID D6RQL4_COPC7 Unreviewed; 1167 AA.
AC D6RQL4;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Histone-lysine N-methyltransferase {ECO:0000313|EMBL:EFI26627.1};
GN ORFNames=CC1G_15399 {ECO:0000313|EMBL:EFI26627.1};
OS Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS (Inky cap fungus) (Hormographiella aspergillata).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Coprinopsis.
OX NCBI_TaxID=240176 {ECO:0000313|EMBL:EFI26627.1, ECO:0000313|Proteomes:UP000001861};
RN [1] {ECO:0000313|EMBL:EFI26627.1, ECO:0000313|Proteomes:UP000001861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003
RC {ECO:0000313|Proteomes:UP000001861};
RX PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA Burns C., Canback B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA Kues U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J.,
RA Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA Zolan M.E., Pukkila P.J.;
RT "Insights into evolution of multicellular fungi from the assembled
RT chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFI26627.1}.
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DR EMBL; AACS02000012; EFI26627.1; -; Genomic_DNA.
DR RefSeq; XP_002910121.1; XM_002910075.1.
DR AlphaFoldDB; D6RQL4; -.
DR STRING; 240176.D6RQL4; -.
DR GeneID; 9380070; -.
DR KEGG; cci:CC1G_15399; -.
DR VEuPathDB; FungiDB:CC1G_15399; -.
DR eggNOG; KOG1082; Eukaryota.
DR HOGENOM; CLU_274514_0_0_1; -.
DR InParanoid; D6RQL4; -.
DR OrthoDB; 5481936at2759; -.
DR Proteomes; UP000001861; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR46223:SF3; HISTONE H3 (LYS9) METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR46223; HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000001861};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 991..1128
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 1152..1167
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 693..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1130..1149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..726
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 727..795
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1167 AA; 131752 MW; 4669E94A8794CD1C CRC64;
MGDLSLDMHP TTAVDRFLQV QELMSMVCEI LADDAERGAL YSLARTHWCI HHAAIQCLWR
DIPGLSALIG LFPEGCFRPS KQTDALLTIA RPEYIEIGME RVRRYAPFVK AIGYDPEDGD
IKRALAWTAL HALAEYKSTT LPLFPNVERV TIPLLVHHPA ITVFYTPLVL APSVRSITIL
AQVFLEHGVD TFPDVAECMI TSEALADRLV EASGSLTELR IEATPGSWYL HVHLPIRGLN
SLLTRMPAIS TLRTLDITHL DIESGTLEKL SELQGLEHLS LLLSESSELY EDPSTQWTFP
ALLEITLSST AHDHLEACES FLKKFCAPRL TSFTLRQRFH GHDVTFDDTV FTPLSHCTNP
NNITSIVIKE LGVYYRVDPE DEPFNERAFN LDLESLSAFN NLRNLEISPF TAAELEDSAL
TNALSNWQQL ERLVLKYDIP SETTDSNLTL EGVHAAVQLC PNLSHLTLPC LAEKVPTTVP
TPHPSLVYWN VCTSTISSGR NVAAWLQKAF PSLRHVDSFE SVHKYMMTWN RGGEVDCGEW
AQSAQIFVMV SLWNEVAAIL QSPLEDWGSD GDKDWPVEVI GEEVDYWGKV RHEVAWDGWN
RKDGTNTTWK EEYVDKRQAR FISDWDRRQK TRRRNLAEED EYCSIEVHTG LDIHNTETRL
RAQAYEEKLA IAKKYPCNWA KERVKIIQER EESLGMSKRK RSPEGHSESR KLRETAERRK
HRESSVSHSV TSSSRAPSSS QAPVSSASTS TSTSRSATVT SASSPTPTLL ATRASSKLRT
SPSESLSSLW SQEVPLPQRW SKPPLSEKAR GKQPVKETFP SPKLNRAYVE ICSPKHIQAQ
LRRKSKRQLL SEEWSEKAGF SITFVNEVDD EEIPSLPAGF EYREQGYKFS DDIEKPGPDW
FTTCECERNC KSPHACNHRT YVLDEEENKI FAYDSKGLFR FDRIPRGTEV IECNEVSKRS
SLSEKGAHLF AQRCPCDDSC RNRVVQRPKT QPIVIFKTKK CGWGVRSTKN VRRGQVLGTY
TGCSFLNPVP EHRTRERANE EELVNYCFDL DGHELFDETS DDEGAGYTVD SWKDGNWTRF
IKGQCLALSG FIPSNVASAF LLQTGMYYVA FVANQDIPAG TEFTFDYNPL RASQQPSSPQ
SSPYTGSQPR TNIVKCRCGS PQCRGTI
//
