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Database: UniProt
Entry: D6TGI4_9CHLR
LinkDB: D6TGI4_9CHLR
Original site: D6TGI4_9CHLR 
ID   D6TGI4_9CHLR            Unreviewed;       514 AA.
AC   D6TGI4;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   25-OCT-2017, entry version 47.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=Krac_12329 {ECO:0000313|EMBL:EFH90696.1};
OS   Ktedonobacter racemifer DSM 44963.
OC   Bacteria; Chloroflexi; Ktedonobacteria; Ktedonobacterales;
OC   Ktedonobacteraceae; Ktedonobacter.
OX   NCBI_TaxID=485913 {ECO:0000313|EMBL:EFH90696.1, ECO:0000313|Proteomes:UP000004508};
RN   [1] {ECO:0000313|EMBL:EFH90696.1, ECO:0000313|Proteomes:UP000004508}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44963 {ECO:0000313|Proteomes:UP000004508};
RX   PubMed=22180814; DOI=10.4056/sigs.2114901;
RA   Chang Y.J., Land M., Hauser L., Chertkov O., Del Rio T.G., Nolan M.,
RA   Copeland A., Tice H., Cheng J.F., Lucas S., Han C., Goodwin L.,
RA   Pitluck S., Ivanova N., Ovchinikova G., Pati A., Chen A.,
RA   Palaniappan K., Mavromatis K., Liolios K., Brettin T., Fiebig A.,
RA   Rohde M., Abt B., Goker M., Detter J.C., Woyke T., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA   Lapidus A.;
RT   "Non-contiguous finished genome sequence and contextual data of the
RT   filamentous soil bacterium Ktedonobacter racemifer type strain (SOSP1-
RT   21).";
RL   Stand. Genomic Sci. 5:97-111(2011).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EFH90696.1}.
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DR   EMBL; ADVG01000001; EFH90696.1; -; Genomic_DNA.
DR   STRING; 485913.Krac_12329; -.
DR   EnsemblBacteria; EFH90696; EFH90696; Krac_12329.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000004508; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000004508};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004508}.
FT   DOMAIN      211    337       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      421    490       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     219    226       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   514 AA;  58344 MW;  B0583F611EA850EC CRC64;
     MNTATIWRST LERLLQHESL DPVTRQWLQE AHLLASQTTE GGAHEEKESL YFSLQVHNDL
     ARDVLTSHWL EVMEEALQEV TGRTIVLEVT HEPGEEPLPV QEEVATPHLA ASTSAAQNGY
     NFYDRSINRS IPHKAARTPE APSYEQNAAS YQSFQAGVAS QQEQWENEQR SGILTNNRLN
     PRYSFDTFIV GNSNRLAHAA SLAVAEAPGE SYNPLFLYGG VGLGKTHLLH AIGQQGVQTG
     LAVLYVSSEQ FTNEIINAIR YRTTEEFRAK YRSVDILLVD DIQFIAGKES TEEEFFHTFN
     SLHEMSKQIV ICSDRPPKAI ASLEERLRSR FEWGLVADIQ PPDLETRMAI LRVKADALHY
     RVPDEIISYI AGRVQTNIRE LEGCLNRLMA YQQLHRVDLT LDVARAAMSS LGADHRETHL
     DGRQIAQAVA DYYRVSFEAM CSKQRDKHIV APRQVAMYLI RQETQISLFE IGQLFGKRDH
     STVLHACEKI ERNLKQNPTL RQDVSTIREQ LLRD
//
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