ID D6V8Q8_9BRAD Unreviewed; 298 AA.
AC D6V8Q8;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Transcriptional regulator, LysR family {ECO:0000313|EMBL:EFI50546.1};
GN ORFNames=AfiDRAFT_2854 {ECO:0000313|EMBL:EFI50546.1};
OS Afipia sp. 1NLS2.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Afipia.
OX NCBI_TaxID=666684 {ECO:0000313|EMBL:EFI50546.1, ECO:0000313|Proteomes:UP000004041};
RN [1] {ECO:0000313|EMBL:EFI50546.1, ECO:0000313|Proteomes:UP000004041}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1NLS2 {ECO:0000313|EMBL:EFI50546.1,
RC ECO:0000313|Proteomes:UP000004041};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Land M.L., Hauser L., Chang Y.-J., Jeffries C., Prakah O.,
RA Elkins J.G., Brown S.D., Palumbo A.V., Hemme C., Zhou J., Watson D.B.,
RA Jardine P.M., Kostka J.E., Green S.J., Woyke T.J.;
RT "The draft genome of Afipia sp. 1NLS2.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: NodD regulates the expression of the nodABCFE genes which
CC encode other nodulation proteins. NodD is also a negative regulator of
CC its own expression. Binds flavonoids as inducers.
CC {ECO:0000256|ARBA:ARBA00003502}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFI50546.1}.
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DR EMBL; ADVZ01000004; EFI50546.1; -; Genomic_DNA.
DR RefSeq; WP_009340218.1; NZ_ADVZ01000004.1.
DR AlphaFoldDB; D6V8Q8; -.
DR eggNOG; COG0583; Bacteria.
DR Proteomes; UP000004041; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08417; PBP2_Nitroaromatics_like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR037402; YidZ_PBP2.
DR PANTHER; PTHR30118; HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO-RELATED; 1.
DR PANTHER; PTHR30118:SF15; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Nodulation {ECO:0000256|ARBA:ARBA00022458};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 6..63
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 298 AA; 34280 MW; FA0FD117DB3B9FD8 CRC64;
MNLRNIDLNL LTVFDAILSE RSLTRASAKL NMTQPALSNA LARLRTTLDD QLFIRTAQGM
MPTARAKQLA APIRQALDLI QNGLRKQEAF EFETATRKFV IAISDYGEAV IMPRFVDWLA
TVAPHIQVQI RPELGRHIKE ELRDGSIDLA TDYFKIEGDE FRNIHVMDEH LVSMVRQDHP
TIGDHLSIED YLSIPHVVLK QDKPIVDVVL KKHGLTRDIA LQVPHFLSMP LIVQKTDFIC
TLPKRMALVY ADFFRTKVMK TPLEFPNIPI YFMWHQSVDD DLGHRWLRNA LAELCHRL
//
