ID D6WJY6_TRICA Unreviewed; 1220 AA.
AC D6WJY6;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 2.
DT 24-JAN-2024, entry version 63.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFA03920.2};
GN Name=AUGUSTUS-3.0.2_14056 {ECO:0000313|EMBL:EFA03920.2};
GN ORFNames=TcasGA2_TC014056 {ECO:0000313|EMBL:EFA03920.2};
OS Tribolium castaneum (Red flour beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrionidae incertae sedis; Tribolium.
OX NCBI_TaxID=7070 {ECO:0000313|EMBL:EFA03920.2, ECO:0000313|Proteomes:UP000007266};
RN [1] {ECO:0000313|EMBL:EFA03920.2, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:EFA03920.2,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=18362917; DOI=10.1038/nature06784;
RG Tribolium Genome Sequencing Consortium;
RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R.,
RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M.,
RA Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S.,
RA Schroder R., Tautz D., Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M.,
RA Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D.,
RA Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H.,
RA Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A.,
RA Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V.,
RA Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J.,
RA Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S.,
RA Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B.,
RA Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R.,
RA Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L.,
RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y.,
RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G.,
RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J.,
RA Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V.,
RA Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S.,
RA Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B.,
RA Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W.,
RA Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V.,
RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M.,
RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M.,
RA Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D.,
RA Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E.,
RA Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M.,
RA Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N.,
RA Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C.,
RA Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H.,
RA Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M.,
RA Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R.,
RA Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J.,
RA Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B.,
RA Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C.,
RA Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B.,
RA Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H.,
RA Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y.,
RA Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P.,
RA Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S.,
RA Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W.,
RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.;
RT "The genome of the model beetle and pest Tribolium castaneum.";
RL Nature 452:949-955(2008).
RN [2] {ECO:0000313|EMBL:EFA03920.2, ECO:0000313|Proteomes:UP000007266}
RP GENOME REANNOTATION.
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:EFA03920.2,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=19820115; DOI=10.1093/nar/gkp807;
RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W.,
RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.;
RT "BeetleBase in 2010: revisions to provide comprehensive genomic information
RT for Tribolium castaneum.";
RL Nucleic Acids Res. 38:D437-D442(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ971342; EFA03920.2; -; Genomic_DNA.
DR RefSeq; XP_008193143.1; XM_008194921.2.
DR AlphaFoldDB; D6WJY6; -.
DR STRING; 7070.D6WJY6; -.
DR EnsemblMetazoa; TC014056_001; TC014056_001; TC014056.
DR GeneID; 663177; -.
DR KEGG; tca:663177; -.
DR eggNOG; ENOG502QPJ1; Eukaryota.
DR HOGENOM; CLU_008316_0_0_1; -.
DR InParanoid; D6WJY6; -.
DR OMA; GGRFFHN; -.
DR OrthoDB; 2918730at2759; -.
DR Proteomes; UP000007266; Linkage group 5.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR039190; TTC14.
DR PANTHER; PTHR23184; TETRATRICOPEPTIDE REPEAT PROTEIN 14; 1.
DR PANTHER; PTHR23184:SF9; TETRATRICOPEPTIDE REPEAT PROTEIN 14; 1.
DR Pfam; PF07719; TPR_2; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007266};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 304..337
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 338..371
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 379..412
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 462..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 725..882
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 898..1192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..485
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..560
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..652
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 769..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 786..804
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..965
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 966..982
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1066..1163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1220 AA; 138880 MW; 7A0BDBE488ED994F CRC64;
MESLNTNLLS QSLNFNGQQM QKLWEAEYGE NDLHRRNVKD VNFQVYSERQ KHLSFQDRGK
RLKLQQFVVK KANMLFATEA SDFEYKPDEG PVSEDTYAIM PPFETFLNVD KQQRLKYFFK
SVKVGDLIIG TIVSKTQSGM MLKVLCTAGP GPNIIYAADI NVKAFCPVAN IIPAVDKKGI
TRSYMMNDSV CCEVIEKIPD SDKMVCCMKG TPRKPNDPER RPPLGLISAD DFPLAYKKAL
DHKNENYDTV LEKSIGFNNP NNISYLAGVV GIKDHCTLMK GLKGRFAENE YANELRQVQA
SKWAYRNVAD GIDHFKAGKH VEAFQCLNKA LNIDPKNVEG LVARGALYAN SGNFQKAIAD
FETALKLNPN HGNARKYMGE TLVALGRSYE EEDKIEEARK SYQSCLSLIP NHEEAQNSLK
FLKNKTSATK NLIEPTELLL PNLSTASKTA DVNDALKQLL KNEDEEKKDK KKKKKSKKRK
NRRHSSSSSS SSSSGSNDSS SSSSSSSSDS SSSSGDSDFK KRKKHRSRSH RREKQSSLSP
LSKRMAMMDQ SHDTPNTYTF NKPAATSAMF DFNLEQPSET QKPADLSYEQ RLRMFLQETK
GDSDYEEKVR KFLEESSKWK KEKRSDEKKK KRKKDRKNKK DSKKKKKEKK LKRKGFDLSE
FEDHKKLRDA IKKELSKGKK SKKHSIPSDD DEYFLQKAGY TKRFIDSLPD LEELESKLNA
YYAMEKESKR SELSESPKRG LLDSPSPTRE QKARQAVAEA AATAGSANKW KMQVASQPPP
STSGSRFKKK PDREEWKEEQ QQQQMMDKRG GGGGGGMASG GKNNNFEESV RKNQQAPVPP
PEKNMSVRKA MAMKEPPPPK RPDSPKNKPK LLPPIPAVNP LVNPGQVVLD KFGNFRLMTP
PELKKGRDDM PPLPPGRRPP EPPGRPRSDS RSPKRHSRSR SRRTRSSSAS RSRSRSYRSR
SRSYYSRSRS RSGSYYSRSR SRSRSYSGDR RRYRRGGFRG RYNDRGTYYK PRFQNPRNNI
RGRGGGGGGG GYYNRDGRYN DREYRGRGRP YNNYNNRGGR RPRGRYQRGG YREYRDRRDY
RSRSRDRSRS MSGSRDRDSD EAMKKAANAE KDNKVNKYAD NEGEQIRHEG PLSEGEDRDD
YTSNEKFVDR EAFGGKWAEK EEGGGQDNGG GGDGDGAKVD KTNIPSESNI EEMDKFLTKV
KKDKKEEMLE RNKDLLKNKS
//
