ID D6XYY1_BACIE Unreviewed; 885 AA.
AC D6XYY1;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN OrderedLocusNames=Bsel_0760 {ECO:0000313|EMBL:ADH98289.1};
OS Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Salisediminibacterium.
OX NCBI_TaxID=439292 {ECO:0000313|EMBL:ADH98289.1, ECO:0000313|Proteomes:UP000000271};
RN [1] {ECO:0000313|EMBL:ADH98289.1, ECO:0000313|Proteomes:UP000000271}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700615 / DSM 15326 / MLS10
RC {ECO:0000313|Proteomes:UP000000271};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Stolz J.;
RT "Complete sequence of Bacillus selenitireducens MLS10.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
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DR EMBL; CP001791; ADH98289.1; -; Genomic_DNA.
DR RefSeq; WP_013171718.1; NC_014219.1.
DR AlphaFoldDB; D6XYY1; -.
DR STRING; 439292.Bsel_0760; -.
DR REBASE; 26447; BseMLSORF760P.
DR KEGG; bse:Bsel_0760; -.
DR eggNOG; COG1002; Bacteria.
DR HOGENOM; CLU_005831_3_0_9; -.
DR OrthoDB; 32195at2; -.
DR Proteomes; UP000000271; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR046818; MmeI_C.
DR InterPro; IPR046819; MmeI_hel.
DR InterPro; IPR046816; MmeI_Mtase.
DR InterPro; IPR046817; MmeI_N.
DR InterPro; IPR046820; MmeI_TRD.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR33841:SF6; DNA METHYLTRANSFERASE A; 1.
DR PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR Pfam; PF20467; MmeI_C; 1.
DR Pfam; PF20465; MmeI_hel; 1.
DR Pfam; PF20473; MmeI_Mtase; 1.
DR Pfam; PF20464; MmeI_N; 1.
DR Pfam; PF20466; MmeI_TRD; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ADH98289.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 15..158
FT /note="MmeI-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF20464"
FT DOMAIN 163..239
FT /note="MmeI-like helicase spacer"
FT /evidence="ECO:0000259|Pfam:PF20465"
FT DOMAIN 317..575
FT /note="MmeI-like DNA-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF20473"
FT DOMAIN 592..805
FT /note="MmeI-like target recognition"
FT /evidence="ECO:0000259|Pfam:PF20466"
FT DOMAIN 807..880
FT /note="MmeI-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20467"
SQ SEQUENCE 885 AA; 103311 MW; F541A1033FFBA0C1 CRC64;
MVIIELEDKI TEIVNKGDYH EFIYEILEIY GTPRATITRL KKGNLNMSKK NDEVHLKRKV
WFKRVENENL FSVFIELERN INSQSTKPRF LIVTDFNTLL AKDIKTDEVL DIQFIDLPKY
FDFFLAWKGI EKAEFERENP ADVKAAERFA RLYNVLSKDN SKIDLFLVRL LFCLFAEDTG
IFRQLSFTNS IKTLTREDGK DLNDFLKDVF RIMDIDKKDR LNDLPEYLNK FPYVNGQLFS
EPHQDLVFSE KSRKLIIEAG ELLDWSQINP DIFGSMIQAV STRDNRSHLG VHYTSVPNIM
KVIKPLFLDN LYKAFNDAYD DDFKLEMLLT RINKIKFFDP ACGSGNFLII AYKEMRRIEI
NIIKRLKEIR GDYLYMPSIT LDQLYGIEID EFAYEVALLS LWIADHQMNE ELNNEIDNAV
RPTLPLNISG NIHRGNALHM NWKNVCPNDP EDEVYVFGNP PYLGHHRQSD THKSDIRRIF
QGVRGNGYLD YICGWFYLGS EFIQNSNTTL AFVSTNSICQ GEQVAILWSE LFLKRINIHF
AYQSFKWSNS ARNNAGVTVV IIGLTAYKTE QNKLFTSYGE RQVKNINAYL IDGENVIVRD
IKKQLYGLPP MLFGNKPSDG GGLIFEFEEY IQAIEKYPYL KKYFRKYIGS DEILKGSYRY
CLWIEEDCYD EIKDNPIISD RMNMVKLNRE KSKAKSTREW ANKPYKFKQI SPFHKQANID
LDSYTIVVPA VSSESRFYIP MDLVSNKDTI LSNRVYGIYG ADIWILGILL SRMHMTWVRA
VAGRLETRYS YSSGVCYNAF PIPEISQKRI NLIEELVLEI LDAREEDGRS LGEIYYPSNM
PNDLLLAHQK LDKVVDRAYK NRDFSGDEER LRLLIELYSK KVNLR
//
