ID D6Y3A1_THEBD Unreviewed; 403 AA.
AC D6Y3A1;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=3'-5' exonuclease {ECO:0000313|EMBL:ADG88976.1};
GN OrderedLocusNames=Tbis_2266 {ECO:0000313|EMBL:ADG88976.1};
OS Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM
OS 10125 / KCTC 9307 / NBRC 14880 / R51).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Thermobispora.
OX NCBI_TaxID=469371 {ECO:0000313|EMBL:ADG88976.1, ECO:0000313|Proteomes:UP000006640};
RN [1] {ECO:0000313|EMBL:ADG88976.1, ECO:0000313|Proteomes:UP000006640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / KCTC 9307 /
RC NBRC 14880 / R51 {ECO:0000313|Proteomes:UP000006640};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Mikhailova N., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F.,
RA Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T.,
RA Wu D., Jando M., Schneider S., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Thermobispora bispora DSM 43833.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001874; ADG88976.1; -; Genomic_DNA.
DR RefSeq; WP_013132509.1; NC_014165.1.
DR AlphaFoldDB; D6Y3A1; -.
DR STRING; 469371.Tbis_2266; -.
DR KEGG; tbi:Tbis_2266; -.
DR eggNOG; COG0349; Bacteria.
DR HOGENOM; CLU_042387_3_0_11; -.
DR OrthoDB; 144122at2; -.
DR Proteomes; UP000006640; Chromosome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06142; RNaseD_exo; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR041605; Exo_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR47649; RIBONUCLEASE D; 1.
DR PANTHER; PTHR47649:SF1; RIBONUCLEASE D; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF18305; DNA_pol_A_exoN; 1.
DR Pfam; PF00570; HRDC; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00341; HRDC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:ADG88976.1};
KW Hydrolase {ECO:0000313|EMBL:ADG88976.1};
KW Nuclease {ECO:0000313|EMBL:ADG88976.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006640}.
FT DOMAIN 222..302
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 298..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 403 AA; 44219 MW; 632408F3B7AB4590 CRC64;
MTQPHVEPLL EPRDGIPPVI ETWPELSAAV DAFARGTGPV AMDAERASGY RYSGRAYLVQ
LRREGAGTAL IDPVACPDLG ELDRVLADAE IVLHAATQDL PCLAELGFRP RRLFDTELAA
RLLGYERVGL ATMVEVVLGL RLEKGHSAAD WSRRPLPEDW LRYAALDVEV LVELRDALYE
QLVESGKLEW ALEEFAAILS APASPPKSDP WRRTSGIHRV RSLRGLAIVR ELWTLRDEIA
READLAPGRV LPDSAIVQAA LEQPRTTKAL TEITAFTGRS ARRHLREWLD AVNRGRTMPE
SALPQPAPPG NGPPPTNRWA DRDPAAAKRL AAARTVLAGL SEEHRVPVEN LLPPDAVRKL
TWSPPAEITT ETVADRLREL GARRWQVALT AGPLAAELAR LAG
//
