ID D6Z1L0_DESAT Unreviewed; 530 AA.
AC D6Z1L0;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Response regulator receiver modulated metal dependent phosphohydrolase {ECO:0000313|EMBL:ADH85435.1};
GN OrderedLocusNames=DaAHT2_0731 {ECO:0000313|EMBL:ADH85435.1};
OS Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2).
OC Bacteria; Thermodesulfobacteriota; Desulfobulbia; Desulfobulbales;
OC Desulfobulbaceae; Desulfurivibrio.
OX NCBI_TaxID=589865 {ECO:0000313|EMBL:ADH85435.1, ECO:0000313|Proteomes:UP000001508};
RN [1] {ECO:0000313|Proteomes:UP000001508}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19089 / UNIQEM U267 / AHT2
RC {ECO:0000313|Proteomes:UP000001508};
RG US DOE Joint Genome Institute;
RA Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Sorokin D.Y., Muyzer G.,
RA Woyke T.;
RT "Complete sequence of Desulfurivibrio alkaliphilus AHT2.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001940; ADH85435.1; -; Genomic_DNA.
DR AlphaFoldDB; D6Z1L0; -.
DR STRING; 589865.DaAHT2_0731; -.
DR KEGG; dak:DaAHT2_0731; -.
DR eggNOG; COG3437; Bacteria.
DR HOGENOM; CLU_000445_92_10_7; -.
DR InParanoid; D6Z1L0; -.
DR OrthoDB; 9764337at2; -.
DR Proteomes; UP000001508; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00077; HDc; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:ADH85435.1};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Reference proteome {ECO:0000313|Proteomes:UP000001508}.
FT DOMAIN 170..286
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 320..530
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
FT REGION 135..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 299..326
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 219
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 530 AA; 59619 MW; 330142ECA41564CD CRC64;
MNPRVPEHKW NLLDLAVKLL DQSENMVTGC GGLEQESKED LAKINRASKE IMDLIKSLSA
LQAGAGFDVA TARHDLRNPL NNILGYTEML LEDHEENPEV PDFTGQLQEF YVLSRLVLQE
VNKLQQLPLT GYRQGVTPGK PAAAPTPKTP PGRTEAKALQ AIDDRGEKPL ILVVDDITAN
REVLSRRLRR LGYLVMEAEN GRQALAMLET GAFDLVLLDI LMPELDGYEV LRRIKANELI
RHVPVLMISA VGDINSVVRC LEAGADDYLA KPFNSVLLRA RVNASLVKKR LYDQELHYKQ
EIEQHNQLLE QRVRQQVQEI SRAQLAAIFS LSKLAESRDP ETGEHLERFR EYSRVLARHL
QTMPRFCKLI DESFIDNLYA ACPLHDIGKV GIPDAILLKP GRLTAEEFAI MQEHATIGAE
TLLAVDRQYP GSDLIRFGIE IAEGHHERWD GSGYPRGLAG EEIPLVARIV SLADVYDALR
SRRVYKEGMD HATARKIIVE SAGSHFDPVI VEAFLACEDD FQKIWRRIGE
//
