ID   D6Z4R4_DESAT            Unreviewed;       391 AA.
AC   D6Z4R4;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=Iron-containing alcohol dehydrogenase {ECO:0000313|EMBL:ADH86539.1};
GN   OrderedLocusNames=DaAHT2_1858 {ECO:0000313|EMBL:ADH86539.1};
OS   Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2).
OC   Bacteria; Thermodesulfobacteriota; Desulfobulbia; Desulfobulbales;
OC   Desulfobulbaceae; Desulfurivibrio.
OX   NCBI_TaxID=589865 {ECO:0000313|EMBL:ADH86539.1, ECO:0000313|Proteomes:UP000001508};
RN   [1] {ECO:0000313|Proteomes:UP000001508}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19089 / UNIQEM U267 / AHT2
RC   {ECO:0000313|Proteomes:UP000001508};
RG   US DOE Joint Genome Institute;
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Mikhailova N., Sorokin D.Y., Muyzer G.,
RA   Woyke T.;
RT   "Complete sequence of Desulfurivibrio alkaliphilus AHT2.";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001940; ADH86539.1; -; Genomic_DNA.
DR   AlphaFoldDB; D6Z4R4; -.
DR   STRING; 589865.DaAHT2_1858; -.
DR   KEGG; dak:DaAHT2_1858; -.
DR   eggNOG; COG1454; Bacteria.
DR   HOGENOM; CLU_007207_0_0_7; -.
DR   InParanoid; D6Z4R4; -.
DR   OrthoDB; 9778433at2; -.
DR   Proteomes; UP000001508; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:InterPro.
DR   CDD; cd08182; HEPD; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR001670; ADH_Fe/GldA.
DR   InterPro; IPR018211; ADH_Fe_CS.
DR   InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR   InterPro; IPR035873; PhpC.
DR   PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR11496:SF83; HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00465; Fe-ADH; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR   PROSITE; PS00913; ADH_IRON_1; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001508}.
FT   DOMAIN          21..345
FT                   /note="Alcohol dehydrogenase iron-type/glycerol
FT                   dehydrogenase GldA"
FT                   /evidence="ECO:0000259|Pfam:PF00465"
SQ   SEQUENCE   391 AA;  41988 MW;  4FD81470D7C17E8B CRC64;
     MNLSAVNQPY TLATPWRFHN PVQVHFGRDC RRQAVAELAA ARCLIVTSQR GRRQLSDDPW
     LRPLAANPNH LWVDGISENP DLLYLQGEID RLAGQSFEAV LAFGGGSSLD GAKALALALA
     EQGSKYLLRD LLANQELYRQ VRPKPLYAIP TTAGTGSEVT PYATIWDHAA KQKHSLAGPA
     IFPHAAFVDP ALTDSLPAGI TLSTGLDAIN QAAESIWNRN ANPVSLGYAI RALQLGLPAL
     PPLAAGKGEA THRDQLAECS LLAGLAISHT RTALCHSISY PLTAHFGVPH GLACAFTMPA
     VLRFSLQADD GRFSEAAKAL LGPAAKPADL EQLLAALHRQ LQVGEKVKAK IPNRQALLAL
     QKEMITPDRA GNILAPLEPT TLQRILTESW G
//