ID D6Z5H9_DESAT Unreviewed; 420 AA.
AC D6Z5H9;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Integrase family protein {ECO:0000313|EMBL:ADH86716.1};
GN OrderedLocusNames=DaAHT2_2042 {ECO:0000313|EMBL:ADH86716.1};
OS Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2).
OC Bacteria; Thermodesulfobacteriota; Desulfobulbia; Desulfobulbales;
OC Desulfobulbaceae; Desulfurivibrio.
OX NCBI_TaxID=589865 {ECO:0000313|EMBL:ADH86716.1, ECO:0000313|Proteomes:UP000001508};
RN [1] {ECO:0000313|Proteomes:UP000001508}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19089 / UNIQEM U267 / AHT2
RC {ECO:0000313|Proteomes:UP000001508};
RG US DOE Joint Genome Institute;
RA Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Sorokin D.Y., Muyzer G.,
RA Woyke T.;
RT "Complete sequence of Desulfurivibrio alkaliphilus AHT2.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
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DR EMBL; CP001940; ADH86716.1; -; Genomic_DNA.
DR RefSeq; WP_013164235.1; NC_014216.1.
DR AlphaFoldDB; D6Z5H9; -.
DR STRING; 589865.DaAHT2_2042; -.
DR KEGG; dak:DaAHT2_2042; -.
DR eggNOG; COG0582; Bacteria.
DR HOGENOM; CLU_027562_0_0_7; -.
DR InParanoid; D6Z5H9; -.
DR OrthoDB; 9775880at2; -.
DR Proteomes; UP000001508; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR CDD; cd00801; INT_P4_C; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 3.30.160.390; Integrase, DNA-binding domain; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR038488; Integrase_DNA-bd_sf.
DR InterPro; IPR025166; Integrase_DNA_bind_dom.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF13356; Arm-DNA-bind_3; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00023195};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000001508};
KW Viral genome integration {ECO:0000256|ARBA:ARBA00023195};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 100..181
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 204..394
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 420 AA; 47530 MW; 1105CEF1F3BF4584 CRC64;
MTLTDAQVRN VKAEDKTRRL FDGGGLYLEV APSGGKWWRF KYRFPGQGKI QEKRLSLGTY
PGVGLKEARA KRDEMRRQIA QGIDPANLRR STRGSGALAG SFEAVARLWH RNNSTDWAPS
HSTRLIRRLE AHVFPYLGNR PVGDITAPDL MNVLERIKNS GHTETARRIQ TICGQVFRYA
VQKGFAEYDP SSALKGCLGK TTAKNMATIT EPAEVGRLLQ AIDEYPGTQV VRCALQLAPL
FFVRSGELRN ARWDEFDLVN REWKIPVERM KMRQDEKRAR QGQVGHIVPL ATQAVKILEE
ELRPLTGRCA LVFPGLRSRD RAISDATLTN ALRRMGYTGD EMTIHGLRHM ASTLLHGLGF
QSLVIERQLA HKDRNRIRGV YNQADYLEER RRMMQSWADY LGQLKAGKAE KVVPINRLAG
//
