ID D6ZVF5_BIFLJ Unreviewed; 710 AA.
AC D6ZVF5;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN OrderedLocusNames=BLJ_1417 {ECO:0000313|EMBL:ADH00861.1};
OS Bifidobacterium longum subsp. longum (strain JDM301).
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=759350 {ECO:0000313|EMBL:ADH00861.1, ECO:0000313|Proteomes:UP000006740};
RN [1] {ECO:0000313|EMBL:ADH00861.1, ECO:0000313|Proteomes:UP000006740}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JDM301 {ECO:0000313|EMBL:ADH00861.1,
RC ECO:0000313|Proteomes:UP000006740};
RX PubMed=20525832; DOI=10.1128/JB.00538-10;
RA Wei Y.X., Zhang Z.Y., Liu C., Zhu Y.Z., Zhu Y.Q., Zheng H., Zhao G.P.,
RA Wang S., Guo X.K.;
RT "Complete genome sequence of Bifidobacterium longum JDM301.";
RL J. Bacteriol. 192:4076-4077(2010).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002010; ADH00861.1; -; Genomic_DNA.
DR AlphaFoldDB; D6ZVF5; -.
DR CAZy; GH20; Glycoside Hydrolase Family 20.
DR KEGG; bll:BLJ_1417; -.
DR HOGENOM; CLU_020160_0_0_11; -.
DR Proteomes; UP000006740; Chromosome.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06565; GH20_GcnA-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ADH00861.1}.
FT DOMAIN 21..177
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 181..426
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 335
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 710 AA; 79320 MW; 93809A17D74D0016 CRC64;
MKGTAVPTFE YTVDAATLCL TLIPAPMTLE YTHGTAMIRS LVTIEKRIPE YAATEGADET
WETLPIEQLS SELERYCGVT VRTRRVRAAT GEDDASANAA EDARDARAGA PAAMNGTVIS
LGLDSRLAHD EYTLDVFASD TIAVRGGGES GLRYGLQTLR QIIGQTSRAI PCLHIQDKPA
FAVRAYSLDV TRGRVPTMEF LTWFVDQLAL YKYNQFQLYV EHAFAFVELS EAWRGTDPLT
AADITYLDEY CARRGIELVP SLATFGHMYM NLRTREHRGL GEFPEDADRP FSFIERMEHH
TLNAADPKAH DFASRLIEEY APLFRSKSFN IGGDETFDLG RGRSAQDAPE AGRDELYAGF
VRDLCETLAR HGRQPMLWAD IALESPRTMD LLPGDITMLN WMYEPQIDES NIQTIAAQGR
RQFVCPAVRA WSRFFPDYAG AWLNTYHMAL AGVKYGAEGM VVTDWGDYGH VNDPRLSVPG
LCYGAQNAWN PIEIDAHEMN RRISVLVYGD ESGRIMDGLV RIDSDGVSFP WDLAVQVLEL
EYGSGTGMLN TDVASYVERS CGGELVFDRT LGCADARRRL LLRNHARLER RRDCDRALID
CGSAVVAVLD GSAREGLNPE LLWVMLDGQR LFNRLGEELL VLAGGEDACD TKDVTGRALD
ASRRARLAAD LELWFERYRV QWLSIGRYAE LARIAHVVWS FADILRRGAL
//
