ID D7A753_STAND Unreviewed; 1011 AA.
AC D7A753;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Sarcosine oxidase, alpha subunit family {ECO:0000313|EMBL:ADH90284.1};
GN OrderedLocusNames=Snov_3009 {ECO:0000313|EMBL:ADH90284.1};
OS Starkeya novella (strain ATCC 8093 / DSM 506 / JCM 20403 / CCM 1077 / IAM
OS 12100 / NBRC 12443 / NCIMB 10456).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Xanthobacteraceae; Ancylobacter.
OX NCBI_TaxID=639283 {ECO:0000313|EMBL:ADH90284.1, ECO:0000313|Proteomes:UP000006633};
RN [1] {ECO:0000313|EMBL:ADH90284.1, ECO:0000313|Proteomes:UP000006633}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8093 / DSM 506 / JCM 20403 / CCM 1077 / IAM 12100 / NBRC
RC 12443 / NCIMB 10456 {ECO:0000313|Proteomes:UP000006633};
RX PubMed=23450099; DOI=10.4056/sigs.3006378;
RA Kappler U., Davenport K., Beatson S., Lucas S., Lapidus A., Copeland A.,
RA Berry K.W., Glavina Del Rio T., Hammon N., Dalin E., Tice H., Pitluck S.,
RA Richardson P., Bruce D., Goodwin L.A., Han C., Tapia R., Detter J.C.,
RA Chang Y.J., Jeffries C.D., Land M., Hauser L., Kyrpides N.C., Goker M.,
RA Ivanova N., Klenk H.P., Woyke T.;
RT "Complete genome sequence of the facultatively chemolithoautotrophic and
RT methylotrophic alpha Proteobacterium Starkeya novella type strain (ATCC
RT 8093(T)).";
RL Stand. Genomic Sci. 7:44-58(2012).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; CP002026; ADH90284.1; -; Genomic_DNA.
DR RefSeq; WP_013167787.1; NC_014217.1.
DR AlphaFoldDB; D7A753; -.
DR STRING; 639283.Snov_3009; -.
DR KEGG; sno:Snov_3009; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0446; Bacteria.
DR HOGENOM; CLU_011963_0_0_5; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000006633; Chromosome.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 172..431
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 530..612
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 628..893
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 918..1003
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 1011 AA; 108286 MW; B7BF2B33A9D4D4A6 CRC64;
MTNRFRTASG GRIDRTAPVT FRFDGTTYNG FKGDTLASAL IANGVHLVGR SFKYHRPRGF
LSAGSDEPNA LVTVARDAAR SAPNLRATQV ELYDGLKAAS QNRWPSLNFD AGAMNDLFSP
FLPSGFYYKT FMWPAGAWKR FYEPKIRAMA GLGVAPTLPD PDRYTQNYAH CDVLVVGAGP
AGLAAALAAA ESGAKVILAD EQAELGGSLL SESSATIEGE PAAEWLAETL ATLEARDNVT
LLTRTTAFGY FPHNLIALAE RVTEHLAAPD PDLPRERLWQ VRAKEVVLAT GALERPLVFP
DNDRPGVLLA DSGRTYLNRY GAKPGERAVI FTACDAGYRT ALDLATGGVT ISAIADLRAN
LDGELPARAL KAGIDVRPST VVTGTSGRLR VASADLAKVT GGDVASSEKV ACDVVLMSGG
FTPSVHLFSQ SRGKLVWDAA SGAYLPGTSV ERERSAGACR GVYGLQRVLE DGYAQGEAAA
KASRDFASPA RGATPAPAAS SRAFMAQADD LGTDGFIGAT PHGRNRAFAK AFVDWQNDVT
SKDIKLATRE GFRSIEHVKR YTTTGMATDQ GKTSNMNALG IVSEALKEEV PKIGLTTFRP
PFTPTTFGIF AGAARGDLFD PLRKTAIHDW AAEHGAAFED VSMWKRAHYF PKAGEGMHAA
VARECKAVRS SVGMFDASTL GKIEVVGPDA AEFMNRIYTN AWAKLEPGRL RYGVMLREDG
FVMDDGVVGR LAEDRFHVTT TTGGAPRVLA HMEDYLQTEW PDLDVWLTST TEQWAVIAVQ
GPNARAVLQP LIEGIDLSKD AFPHMSVREG RICGVPTRLF SVSFTGELGF EVNVPAEYGR
FVWEAIFAAG EPFGITPYGT ETMHVLRAEK GYIIVGQETD GTATPDDVNL GWAVGKAKKD
FVGKRSLARA SMSAPDRKQL VGLLTKEPAI VLEEGAQIVA DPGAPVPVPM LGHVTSSYPS
STLGRSIALA VIKGGRARIG ETLFVAMPDR AIAVELVEPS FYDPKGERLN A
//
