ID D7A9Y1_STAND Unreviewed; 367 AA.
AC D7A9Y1;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=3-isopropylmalate dehydrogenase {ECO:0000313|EMBL:ADH88907.1};
DE EC=1.1.1.85 {ECO:0000313|EMBL:ADH88907.1};
GN OrderedLocusNames=Snov_1601 {ECO:0000313|EMBL:ADH88907.1};
OS Starkeya novella (strain ATCC 8093 / DSM 506 / JCM 20403 / CCM 1077 / IAM
OS 12100 / NBRC 12443 / NCIMB 10456).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Xanthobacteraceae; Ancylobacter.
OX NCBI_TaxID=639283 {ECO:0000313|EMBL:ADH88907.1, ECO:0000313|Proteomes:UP000006633};
RN [1] {ECO:0000313|EMBL:ADH88907.1, ECO:0000313|Proteomes:UP000006633}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8093 / DSM 506 / JCM 20403 / CCM 1077 / IAM 12100 / NBRC
RC 12443 / NCIMB 10456 {ECO:0000313|Proteomes:UP000006633};
RX PubMed=23450099; DOI=10.4056/sigs.3006378;
RA Kappler U., Davenport K., Beatson S., Lucas S., Lapidus A., Copeland A.,
RA Berry K.W., Glavina Del Rio T., Hammon N., Dalin E., Tice H., Pitluck S.,
RA Richardson P., Bruce D., Goodwin L.A., Han C., Tapia R., Detter J.C.,
RA Chang Y.J., Jeffries C.D., Land M., Hauser L., Kyrpides N.C., Goker M.,
RA Ivanova N., Klenk H.P., Woyke T.;
RT "Complete genome sequence of the facultatively chemolithoautotrophic and
RT methylotrophic alpha Proteobacterium Starkeya novella type strain (ATCC
RT 8093(T)).";
RL Stand. Genomic Sci. 7:44-58(2012).
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
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DR EMBL; CP002026; ADH88907.1; -; Genomic_DNA.
DR AlphaFoldDB; D7A9Y1; -.
DR STRING; 639283.Snov_1601; -.
DR KEGG; sno:Snov_1601; -.
DR eggNOG; COG0473; Bacteria.
DR HOGENOM; CLU_031953_0_1_5; -.
DR Proteomes; UP000006633; Chromosome.
DR GO; GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:ADH88907.1}.
FT DOMAIN 10..355
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 367 AA; 39082 MW; F1D40721AFD35B7A CRC64;
MPDRNNGTLR IGVLEGDDIG HEIVPAAQRV AAAAASAAGL SVDWRPIPIG RRALDELGHT
MPPGTLETLG TLDGFILGPI GHQAYPKVPA AINPHPILRK HFDLFANVRP TRSYPGLGCL
YDDIDLVIIR ENNEGFQPDR NVVAGSGEFR PTHDTTISVR VITRDGSRKV ARAALEIARS
RKKRLTVVHK DTVFKLGCGM FVEECYAAGE EFPDVTIDEV IVDTFAMKLV REPQRFDTVV
TTNMFGDILT DEAAGLVGGL GMAPGLCIGR GDIAMAQATH GSAPDIAGKG IANPYAMIES
TRMLVEWLGR KRGIAAAERA AALMKAAIEA ALADPATRTP DIRGTGTQAD MVGGMISAME
TFGHAAA
//
