ID   D7ASH6_THEM3            Unreviewed;       349 AA.
AC   D7ASH6;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Cobalamin (Vitamin B12) biosynthesis CbiG protein {ECO:0000313|EMBL:ADH60200.1};
GN   OrderedLocusNames=Tmath_0427 {ECO:0000313|EMBL:ADH60200.1};
OS   Thermoanaerobacter mathranii subsp. mathranii (strain DSM 11426 / CCUG
OS   53645 / CIP 108742 / A3).
OC   Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Thermoanaerobacter.
OX   NCBI_TaxID=583358 {ECO:0000313|EMBL:ADH60200.1, ECO:0000313|Proteomes:UP000002064};
RN   [1] {ECO:0000313|EMBL:ADH60200.1, ECO:0000313|Proteomes:UP000002064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11426 / CIP 108742 / A3
RC   {ECO:0000313|Proteomes:UP000002064};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Held B., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Zhou J., Hemme C., Woyke T.;
RT   "Complete sequence of Thermoanaerobacter mathranii subsp. mathranii
RT   mathranii str. A3.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002032; ADH60200.1; -; Genomic_DNA.
DR   RefSeq; WP_013149809.1; NC_014209.1.
DR   AlphaFoldDB; D7ASH6; -.
DR   STRING; 583358.Tmath_0427; -.
DR   KEGG; tmt:Tmath_0427; -.
DR   HOGENOM; CLU_028397_0_0_9; -.
DR   Proteomes; UP000002064; Chromosome.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.11220; -; 1.
DR   Gene3D; 3.30.420.180; CobE/GbiG C-terminal domain; 1.
DR   InterPro; IPR021745; CbiG_mid.
DR   InterPro; IPR021744; CbiG_N.
DR   InterPro; IPR002750; CobE/GbiG_C.
DR   InterPro; IPR036518; CobE/GbiG_C_sf.
DR   InterPro; IPR038029; GbiG_N_sf.
DR   PANTHER; PTHR37477; COBALT-PRECORRIN-5A HYDROLASE; 1.
DR   PANTHER; PTHR37477:SF1; COBALT-PRECORRIN-5A HYDROLASE; 1.
DR   Pfam; PF01890; CbiG_C; 1.
DR   Pfam; PF11761; CbiG_mid; 1.
DR   Pfam; PF11760; CbiG_N; 1.
DR   SUPFAM; SSF159672; CbiG N-terminal domain-like; 1.
DR   SUPFAM; SSF159664; CobE/GbiG C-terminal domain-like; 1.
PE   4: Predicted;
FT   DOMAIN          48..128
FT                   /note="Cobalamin synthesis G N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11760"
FT   DOMAIN          133..215
FT                   /note="Cobalamin biosynthesis central region"
FT                   /evidence="ECO:0000259|Pfam:PF11761"
FT   DOMAIN          218..334
FT                   /note="CobE/GbiG C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01890"
SQ   SEQUENCE   349 AA;  38775 MW;  4BAB9A2054EDF25B CRC64;
     MKVAIIALTK NASKLANEIG QKLKGDVYVK EKYSTPEGYA IEEDFIDFVH KIFRKYQGLV
     FVMATGIVVR AIAGVVKDKF TDPAVVVVDE KGKFAISLLS GHVGGANRLA LKVASIIGAQ
     PVITTATDVE GVISLDVIAK DYGYQIENKE DLKKVSAAFV NGENVRFILD EDAEKIPLLK
     DYLKNRDDRQ VDAFVYITDK EIKKPLEKPY VILRPKNIVI GLGCKKGIAF EDLFLFVSET
     FKKLNLSLKS IKSIATIDIK KEEKGIQHLA KFLKVPLVFY TKEDLKKVED KFPISDFVFH
     TVGVGSVARP SAYLASSGGK EIAYLKKNGM TLAIYKKEGL TWDGLKSWE
//