ID D7B2N0_NOCDD Unreviewed; 382 AA.
AC D7B2N0;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN OrderedLocusNames=Ndas_1290 {ECO:0000313|EMBL:ADH66728.1};
OS Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / CIP 107115 / JCM
OS 7437 / KCTC 9190 / NBRC 14626 / NCTC 10488 / NRRL B-5397 / IMRU 509)
OS (Actinomadura dassonvillei).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=446468 {ECO:0000313|EMBL:ADH66728.1, ECO:0000313|Proteomes:UP000002219};
RN [1] {ECO:0000313|EMBL:ADH66728.1, ECO:0000313|Proteomes:UP000002219}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23218 / DSM 43111 / CIP 107115 / JCM 7437 / KCTC 9190 /
RC NBRC 14626 / NCTC 10488 / NRRL B-5397 / IMRU 509
RC {ECO:0000313|Proteomes:UP000002219};
RX PubMed=21304737; DOI=10.4056/sigs.1363462;
RA Sun H., Lapidus A., Nolan M., Lucas S., Del Rio T.G., Tice H., Cheng J.F.,
RA Tapia R., Han C., Goodwin L., Pitluck S., Pagani I., Ivanova N.,
RA Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K., Land M.,
RA Hauser L., Chang Y.J., Jeffries C.D., Djao O.D., Rohde M., Sikorski J.,
RA Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU
RT 509).";
RL Stand. Genomic Sci. 3:325-336(2010).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002040; ADH66728.1; -; Genomic_DNA.
DR RefSeq; WP_013152335.1; NC_014210.1.
DR AlphaFoldDB; D7B2N0; -.
DR STRING; 446468.Ndas_1290; -.
DR KEGG; nda:Ndas_1290; -.
DR eggNOG; COG2518; Bacteria.
DR HOGENOM; CLU_037629_0_1_11; -.
DR OrthoDB; 4035289at2; -.
DR Proteomes; UP000002219; Chromosome 1.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:ADH66728.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002219};
KW Transferase {ECO:0000313|EMBL:ADH66728.1}.
SQ SEQUENCE 382 AA; 42415 MW; CA3E3C5F7AFD8939 CRC64;
MLPQHEKLVS RLTQAGNLDQ HWHGAFAAVE RHRFLPGRIT APDGTTVDRD GDHDGDRERW
LELAYDDIPV ITQVDDGTGE GSGYPASSAS QPSIVADMLH RLDVFPGMRV LEVGTGTGYN
AGLLSHRLGG ENVTTVEIDA DLAEQARVRL LDAGFAAHVV TGDGTRGWPK RAPYDRVLST
AAVQRVPYAW VAQSRPGGRI LTPWGTAFHN GALAELRVGP DGSARGHFAG DVAFMWVRDQ
RIPRRVVETH VRPEEQEFTR SRTGLHPYEP ISDFSASFAI GLHMPTVLNR VEYTDEEQRF
TVHLVDPGTG SWASWHVDPD RGETGYEVHQ HGPRRLFSEL EAAYTWWQEE GPPEHTRFGL
TVSAERQNAW LDHEGRPVLT AP
//
