ID   D7B438_NOCDD            Unreviewed;       498 AA.
AC   D7B438;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   RecName: Full=D,D-heptose 1,7-bisphosphate phosphatase {ECO:0000256|ARBA:ARBA00031828};
GN   OrderedLocusNames=Ndas_1570 {ECO:0000313|EMBL:ADH66999.1};
OS   Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / CIP 107115 / JCM
OS   7437 / KCTC 9190 / NBRC 14626 / NCTC 10488 / NRRL B-5397 / IMRU 509)
OS   (Actinomadura dassonvillei).
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Nocardiopsaceae; Nocardiopsis.
OX   NCBI_TaxID=446468 {ECO:0000313|EMBL:ADH66999.1, ECO:0000313|Proteomes:UP000002219};
RN   [1] {ECO:0000313|EMBL:ADH66999.1, ECO:0000313|Proteomes:UP000002219}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23218 / DSM 43111 / CIP 107115 / JCM 7437 / KCTC 9190 /
RC   NBRC 14626 / NCTC 10488 / NRRL B-5397 / IMRU 509
RC   {ECO:0000313|Proteomes:UP000002219};
RX   PubMed=21304737; DOI=10.4056/sigs.1363462;
RA   Sun H., Lapidus A., Nolan M., Lucas S., Del Rio T.G., Tice H., Cheng J.F.,
RA   Tapia R., Han C., Goodwin L., Pitluck S., Pagani I., Ivanova N.,
RA   Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K., Land M.,
RA   Hauser L., Chang Y.J., Jeffries C.D., Djao O.D., Rohde M., Sikorski J.,
RA   Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU
RT   509).";
RL   Stand. Genomic Sci. 3:325-336(2010).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the GmhB family.
CC       {ECO:0000256|ARBA:ARBA00005628}.
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DR   EMBL; CP002040; ADH66999.1; -; Genomic_DNA.
DR   RefSeq; WP_013152606.1; NC_014210.1.
DR   AlphaFoldDB; D7B438; -.
DR   STRING; 446468.Ndas_1570; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   KEGG; nda:Ndas_1570; -.
DR   eggNOG; COG0241; Bacteria.
DR   eggNOG; COG1216; Bacteria.
DR   HOGENOM; CLU_546152_0_0_11; -.
DR   OrthoDB; 9781367at2; -.
DR   Proteomes; UP000002219; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR006439; HAD-SF_hydro_IA.
DR   InterPro; IPR006549; HAD-SF_hydro_IIIA.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR004446; Heptose_bisP_phosphatase.
DR   InterPro; IPR006543; Histidinol-phos.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   NCBIfam; TIGR01509; HAD-SF-IA-v3; 1.
DR   NCBIfam; TIGR01662; HAD-SF-IIIA; 1.
DR   NCBIfam; TIGR01656; Histidinol-ppas; 1.
DR   PANTHER; PTHR42891; D-GLYCERO-BETA-D-MANNO-HEPTOSE-1,7-BISPHOSPHATE 7-PHOSPHATASE; 1.
DR   PANTHER; PTHR42891:SF1; D-GLYCERO-BETA-D-MANNO-HEPTOSE-1,7-BISPHOSPHATE 7-PHOSPHATASE; 1.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   Pfam; PF13242; Hydrolase_like; 1.
DR   SUPFAM; SSF56784; HAD-like; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Hydrolase {ECO:0000313|EMBL:ADH66999.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002219}.
FT   DOMAIN          7..129
FT                   /note="Glycosyltransferase 2-like"
FT                   /evidence="ECO:0000259|Pfam:PF00535"
SQ   SEQUENCE   498 AA;  52507 MW;  B96D67564AD05767 CRC64;
     MSAPRYSVVV PTMGRDTLPR VLEPLLDAPP REAPEEVVVV DDRPPDDTEP LPGTDHARVR
     VLRTGGGGPA AARQAGWHAC ATEWIAFLDD DVAPPADWPR RLRADLADLP AEVGASQGRI
     TVPRPRGHRP TDAERATLAL EGARWITADM AYRRSALEAV GGFDARFPRA YREDTDLALR
     VVGAGFVLVP GERECVHPLR SGGRWASLAA QRGNADNALM DRLHGRGWRN RVGEGPGGLR
     GHVLTTAALL GAAGAALTGR RAAAAACAAL WTARTAAFAR RRIRGGPATR DEVTDMLVTS
     ALIPPLACWQ RLRGEIRHAG ARPAPGVAAV LFDRDGTLVE DVPYNGDPDK VRPTPSAERA
     LALARGAGLA VGVVSNQSGI ARGLITRDQV DAVNRRVEEL LGPFDVWRVC PHGEEDGCGC
     RKPAPGMVRS AAAELGLPPS RCALVGDIGA DVDAARAAGA RGVLVPTAAT LDAECRSAPE
     TAPDLEAAVL RLLGRDAS
//