ID D7C4F1_STRBB Unreviewed; 670 AA.
AC D7C4F1;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Glycoside hydrolase family 20, catalytic core {ECO:0000313|EMBL:ADI03973.1};
GN OrderedLocusNames=SBI_00852 {ECO:0000313|EMBL:ADI03973.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI03973.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI03973.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI03973.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; CP002047; ADI03973.1; -; Genomic_DNA.
DR AlphaFoldDB; D7C4F1; -.
DR STRING; 749414.SBI_00852; -.
DR CAZy; GH20; Glycoside Hydrolase Family 20.
DR KEGG; sbh:SBI_00852; -.
DR PATRIC; fig|749414.3.peg.871; -.
DR eggNOG; COG3525; Bacteria.
DR HOGENOM; CLU_010969_0_1_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR43678:SF1; BETA-N-ACETYLHEXOSAMINIDASE; 1.
DR PANTHER; PTHR43678; PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00640)-RELATED; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR Pfam; PF14200; RicinB_lectin_2; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ADI03973.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000377};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..670
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038999590"
FT DOMAIN 45..182
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 231..477
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT DOMAIN 566..651
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|Pfam:PF14200"
FT ACT_SITE 326
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 670 AA; 72679 MW; 2FA40BFF412A2108 CRC64;
MRAGRGRRRW AVCLLAALAL FVPPALPASA HAPTSAAAAR AAATPEVIPA LTGWTAGSGT
LQLQQGSRIV SPAAKRVPAE RAPAKRAPIK RAQADAATFA DDLAAATGLR LPVVSGGEPR
AGDLVLRLDP GARELGAEGY ELLVSDTVRI TGATDDGLFL GTRTVLQMLH GQTVLPRGRT
VDVPQYPERG VGVCACYIHI SMPWFERLMR EMSYLKLNQL WIEAKVASDD YPKTKFWGYY
TKDEIRQLSA MAKKYHITLV PEINSPGHID PYLQNHPELQ LTDSSGAKSP SRLDITRPEA
YSFYTGLLDE ALTVWDTPYW HMGADEYMLG SDYAAYPQIA AYAKAKYGAS ATPQDAFIDF
VNRVNAHVRA DGRTLRIWND GLTGENTIAL DKNIDVEHWT PEAQQPPSAL LAQGHQVMNS
AYSLYLIRGG SKMKTQALYD SDWTPLRFEG ETLTGPQPQV TGAKITMWPD FASEQTENEV
EADAFMPLRF ISQATWGSPK PAATYTGFAD LANRLGHTPG WNNVTRLPLK DGTYALTLPD
SAKRLTTAGT TQGAPAKLAA DPDATWALSA TPDGYYRIRA VRGGTTTGNC LDMVSGRRYL
GAPLEAGATI TQQSCSDNTR TQRWQLTTKG DTVTLVNAIS QLGLAQNTDG LAVQMPPDTQ
PPTALRPVAR
//
