ID D7C7G8_STRBB Unreviewed; 471 AA.
AC D7C7G8;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Ricin B lectin {ECO:0000313|EMBL:ADI10522.1};
GN OrderedLocusNames=SBI_07402 {ECO:0000313|EMBL:ADI10522.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI10522.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI10522.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI10522.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC {ECO:0000256|ARBA:ARBA00005382}.
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DR EMBL; CP002047; ADI10522.1; -; Genomic_DNA.
DR RefSeq; WP_014179972.1; NC_016582.1.
DR AlphaFoldDB; D7C7G8; -.
DR STRING; 749414.SBI_07402; -.
DR CAZy; GH30; Glycoside Hydrolase Family 30.
DR KEGG; sbh:SBI_07402; -.
DR PATRIC; fig|749414.3.peg.7613; -.
DR eggNOG; COG5520; Bacteria.
DR HOGENOM; CLU_031530_1_0_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR039514; 6GAL-like.
DR InterPro; IPR033452; GH30_C.
DR InterPro; IPR001139; Glyco_hydro_30.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR Pfam; PF14587; Glyco_hydr_30_2; 1.
DR Pfam; PF17189; Glyco_hydro_30C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lectin {ECO:0000313|EMBL:ADI10522.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000377};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..471
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003093667"
FT DOMAIN 42..242
FT /note="Endo-beta-1,6-galactanase-like"
FT /evidence="ECO:0000259|Pfam:PF14587"
FT DOMAIN 377..467
FT /note="Glycosyl hydrolase family 30 beta sandwich"
FT /evidence="ECO:0000259|Pfam:PF17189"
SQ SEQUENCE 471 AA; 50135 MW; 9380CBC4FA2F41C4 CRC64;
MIKVMRAAVT GALAVALLGT AATVPEAHAG DGTAAGTAGR VDFGQRQQPI DGFGFSQAFQ
RADIMHGARG LTPEHQREVL DLLLDRKSGA GLSILRLGVG SSSDDVYDHM KSIQPTDPGG
PEATPRYEWD GDDGGQVWLA KEAKAYGVKR FYADAWSAPG YMKTNGTDAN GGTLKPEWRQ
AYADYLVQYA KFYRQEGVRI TDVGFTNEPD LSTSYASMQF TPEQAVQTVK ALGPTVRRAG
LNLVCCDAAG WDQQAAFSAA IEADPRAAAL VGVHTGHPYV TPSDQPLPTN RRTWMSEWSP
NGATWNEAWD DGSGYDGLAV AEAIHTTLAD AHASAYVYWF GASIGATRGL IQLDGADYHV
SKRLWALAAY SRFIRPGAVR VAAATEASGV KITAFRNRDG KRVLEILNTG TDTVRTDYAL
TGGGAGGSAR GSVYRTDETH SLSRVGAVDV RGGKLGVELP ARSLTTVVLG S
//
