ID D7CGC1_STRBB Unreviewed; 436 AA.
AC D7CGC1;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Two-component system sensor kinase {ECO:0000313|EMBL:ADI09025.1};
GN OrderedLocusNames=SBI_05905 {ECO:0000313|EMBL:ADI09025.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI09025.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI09025.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI09025.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
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DR EMBL; CP002047; ADI09025.1; -; Genomic_DNA.
DR RefSeq; WP_014178487.1; NC_016582.1.
DR AlphaFoldDB; D7CGC1; -.
DR STRING; 749414.SBI_05905; -.
DR KEGG; sbh:SBI_05905; -.
DR PATRIC; fig|749414.3.peg.6089; -.
DR eggNOG; COG4585; Bacteria.
DR HOGENOM; CLU_000445_20_2_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR025828; Put_sensor_dom.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF13796; Sensor; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ADI09025.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000377};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 25..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..207
FT /note="Putative sensor"
FT /evidence="ECO:0000259|Pfam:PF13796"
FT DOMAIN 235..300
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
SQ SEQUENCE 436 AA; 45626 MW; 98C84F0C008A69FB CRC64;
MSTRNVRQAL YQPGYLRSAW PWRAVLYLMS SAPVGALALL GIVVFALVGG VLTIVVIGLP
VLVALGLAGV PVGAIERRRL RLVDNSPARN PHSAPDEPGL LAWARVRYQE RTTWYELAYT
VLFAFGLWMA DALALLGALG APLAMMATPI LLALDGGGQA QALKYWSVTS YPEASAWSLA
GVLLLPVGLY CLGVFAALRS AFAHLLLVGP EGELREELGE VARSRARLVH AFEAERRRIE
RDLHDGAQQR LVALTMTLGL ARLDAPPGPL ADQLAKAHGE AGKVLAELRE LIHGIHPQVL
ADRGLEAALG DAADRSPVPV LVNASGLGRL PEPVEKAAYF VVCEALANVA KHSAAGLAEV
GAEIREGSLF VSVLDDGVGG AVLLPGGSGG RAGGSGLTGL SDRVAALDGT LRLSSPPGGP
TILSVEIPCE PIEVFG
//
