ID D7DU19_METV3 Unreviewed; 713 AA.
AC D7DU19;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN OrderedLocusNames=Mvol_0972 {ECO:0000313|EMBL:ADI36629.1};
OS Methanococcus voltae (strain ATCC BAA-1334 / A3).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanococcaceae; Methanococcus.
OX NCBI_TaxID=456320 {ECO:0000313|EMBL:ADI36629.1, ECO:0000313|Proteomes:UP000007722};
RN [1] {ECO:0000313|EMBL:ADI36629.1, ECO:0000313|Proteomes:UP000007722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1334 / A3 {ECO:0000313|Proteomes:UP000007722};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Lowry S., Clum A., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Whitman W.B., Woyke T.;
RT "Complete sequence of Methanococcus voltae A3.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; CP002057; ADI36629.1; -; Genomic_DNA.
DR AlphaFoldDB; D7DU19; -.
DR STRING; 456320.Mvol_0972; -.
DR KEGG; mvo:Mvol_0972; -.
DR eggNOG; arCOG00798; Archaea.
DR HOGENOM; CLU_028798_0_0_2; -.
DR InParanoid; D7DU19; -.
DR Proteomes; UP000007722; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ADI36629.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007722}.
FT DOMAIN 296..432
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF00580"
FT DOMAIN 633..690
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13361"
FT REGION 229..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 713 AA; 83453 MW; 7E28B3E9F96B9AF4 CRC64;
MDKLKVKSGF KMGIEVIPDN FYKLTKGETR LLNKMKEIYE NYENEDKTDN FDGNRNCVLY
VQQNVKGTKP DFILIDSFKG ICIFEVKDWK IGYIKKINSH QVQTIDDKTF KNPIVISNSY
FNKMKDIINN DEVFKAFKDK NGILPKIYSY TVFSKIKSKE IADFQMNKVL NQPPSKYITA
DNLTTLTIDK IFDNHNDVKI SNIEFNRLRS LICPEISIYG TKQKIRDKYS KNKDLSNKKS
VQNENKKRKD DEGTKSKKIN SLIKLFKIIN KISSKDAIDD IISYEKDYNE LIKVLDVEQE
KISKKIPSGH FMITGVPGSG KTVILLSRAI FLAKNNPDWK IRVLTYNKTL SEEFKNNLRT
VCTKIGNEDI LNNIEVSTFH KFAKELYFTY NSNYNPTYDN NIENEYNKDT KDTKDKKDDF
KVKFNTESKQ FWNYELPNKV LNLLEQHISE NKPLKLYDAI LIDEYQDFMN EWIKICVNSC
KKYPYEDYTG KTTEGINLFL AGDRLQSIYR LNGQSWKSLG IDMRGRSKLL KSTYRTGKKH
LNLGIDFLMS NEELKNQIYD FYNGTNTFSI LDGNIELLKG KYDVLNDRLK KLLEEYKPEE
IMILCNDNKQ CEKLYNNLDS DLKKKCSFSK NLEFGYVRIL TLHSSKGLES PICLITNLSE
INKSNNKVQD ILNRKLLYVG ITRAFERLIL HSEDFEKNYA KELYDIIIKN EEK
//
