ID D7E791_METEZ Unreviewed; 980 AA.
AC D7E791;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Metev_0946 {ECO:0000313|EMBL:ADI73840.1};
OS Methanohalobium evestigatum (strain ATCC BAA-1072 / DSM 3721 / NBRC 107634
OS / OCM 161 / Z-7303).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanohalobium.
OX NCBI_TaxID=644295 {ECO:0000313|EMBL:ADI73840.1, ECO:0000313|Proteomes:UP000000391};
RN [1] {ECO:0000313|EMBL:ADI73840.1, ECO:0000313|Proteomes:UP000000391}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1072 / DSM 3721 / NBRC 107634 / OCM 161 / Z-7303
RC {ECO:0000313|Proteomes:UP000000391};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Anderson I.,
RA Woyke T.;
RT "Complete sequence chromosome of Methanohalobium evestigatum Z-7303.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP002069; ADI73840.1; -; Genomic_DNA.
DR AlphaFoldDB; D7E791; -.
DR STRING; 644295.Metev_0946; -.
DR KEGG; mev:Metev_0946; -.
DR HOGENOM; CLU_007294_0_0_2; -.
DR Proteomes; UP000000391; Chromosome.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00130; PAS; 5.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.450.20; PAS domain; 5.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF13426; PAS_9; 2.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00086; PAC; 4.
DR SMART; SM00091; PAS; 4.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 5.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000391}.
FT DOMAIN 99..151
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 172..221
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 226..276
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 466..512
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 648..700
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 861..931
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
SQ SEQUENCE 980 AA; 112721 MW; 9A799F9048621AD1 CRC64;
MRRGLNIQKS ESSINQTEAS TIQNVLMDFI NNEVFFVFLF DGTKDRSVQS VSGNITLLGY
KPEQFKPGKL YYNDIIHSVD REYVESEISN CFEKRCSGYN LQYRVLTGEG NIRWVDERTV
VLYGGDGSVD RQESVVFDIT NNKLSEIDLK ASEKKYSTLI ECGIDGILIV QDGYIKFANR
AFENITGYKR DEIIETTFLD YIPVEYQRMV NKKYEKLLKT EPKYPYTYEV YIQSKSEGLI
PVEINLSAIN FEANPAVMFN IRDITERKEA EMKLNLDESC LESLLKINQM SDFSDEEITN
LVLDEMIRLT QSDSGYIVFF NNEDESSSIY VLSKDETNSV SDKQFKNSLK NTGLWNRVIK
QKHPVISNNI SVDFYDEDFY GNLNIKRLLN IPIFDDDSVV AVGGVFNKNK DYDKSNIRQL
TLLLNIMLDI IQKRNTEAAL KSSEKKYSTL VEKGIDGTLI VQDEAIKFAN KAFENITGYK
RDEITETSFL AYIPVEYQRM VLKKYNKTLK ANQDNSRIYE VNFLSSTKNT VPTEINFSPI
HYEGKPAVML NVRDITKQRQ KENELIDTTR MQGLLEDIIN NSPAIVFIWR AEKDWPVEFV
SENIMQFGYI PEDFTSERII YGDIIHPDDL QKVRNKMAGR YEDKSGEFNL EYRILTSNDE
VRWVDERTTI HYDENGNVNY LQGIIIDITK KKQADNFLRI QSDTGSFVSP KGNNLQEIFE
QYLDFCISMD PIDCGGLYLI DEVTNDLNLV SSEGLSSELM QKMSHFTPNS IQHRLFTTGH
PIYKLYSEII SITGNDLPYE SLRATAIIPV RYQDDVVAVM FLASKNNYEI SQDVRISLET
VADQIGETIG YIKYENDFEY NKDNTSKLLD NVDDFIFVID SEGHILYANK ATQDRLGYTE
QELQEMNIIN LHYSKQALKA ASNISDVVSG NRFSCDIPLI AKDGTIIYKD TKFSKGEWYG
QEAIIGVSRE IDENHKSSGD
//
