ID D7E9Q4_METEZ Unreviewed; 164 AA.
AC D7E9Q4;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=CoB/CoM heterodisulfide reductase, subunit C {ECO:0000313|EMBL:ADI74326.1};
DE EC=1.8.98.1 {ECO:0000313|EMBL:ADI74326.1};
GN OrderedLocusNames=Metev_1473 {ECO:0000313|EMBL:ADI74326.1};
OS Methanohalobium evestigatum (strain ATCC BAA-1072 / DSM 3721 / NBRC 107634
OS / OCM 161 / Z-7303).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanohalobium.
OX NCBI_TaxID=644295 {ECO:0000313|EMBL:ADI74326.1, ECO:0000313|Proteomes:UP000000391};
RN [1] {ECO:0000313|EMBL:ADI74326.1, ECO:0000313|Proteomes:UP000000391}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1072 / DSM 3721 / NBRC 107634 / OCM 161 / Z-7303
RC {ECO:0000313|Proteomes:UP000000391};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Anderson I.,
RA Woyke T.;
RT "Complete sequence chromosome of Methanohalobium evestigatum Z-7303.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor metabolism; coenzyme M-coenzyme B heterodisulfide
CC reduction; coenzyme B and coenzyme M from coenzyme M-coenzyme B
CC heterodisulfide: step 1/1. {ECO:0000256|ARBA:ARBA00004808}.
CC -!- SIMILARITY: Belongs to the HdrC family.
CC {ECO:0000256|ARBA:ARBA00007097}.
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DR EMBL; CP002069; ADI74326.1; -; Genomic_DNA.
DR RefSeq; WP_013194891.1; NC_014253.1.
DR AlphaFoldDB; D7E9Q4; -.
DR STRING; 644295.Metev_1473; -.
DR GeneID; 9347113; -.
DR KEGG; mev:Metev_1473; -.
DR HOGENOM; CLU_121273_0_0_2; -.
DR OrthoDB; 144910at2157; -.
DR UniPathway; UPA00647; UER00700.
DR Proteomes; UP000000391; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0051912; F:CoB--CoM heterodisulfide reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR017680; CoB/CoM_hetero-S_Rdtase_csu.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR03290; CoB_CoM_SS_C; 1.
DR PANTHER; PTHR43255:SF1; FERREDOXIN_F(420)H(2)-DEPENDENT COB-COM HETERODISULFIDE REDUCTASE SUBUNIT C; 1.
DR PANTHER; PTHR43255; IRON-SULFUR-BINDING OXIDOREDUCTASE FADF-RELATED-RELATED; 1.
DR Pfam; PF13183; Fer4_8; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW Methanogenesis {ECO:0000256|ARBA:ARBA00022994};
KW Oxidoreductase {ECO:0000313|EMBL:ADI74326.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000391}.
FT DOMAIN 11..41
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 52..82
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 164 AA; 18563 MW; 2024E0FFDF0DE62A CRC64;
MPESDFSEKL KKTGVDILKC MQCGVCSGSC PSGRHMSLNI RKIIKKAYSN DRNILTDKDL
WMCTTCYTCQ ERCPRGIKIV DGVYKIRNVA VREGTMLSEH RKVSHLLLET GHAVPINEET
KQKREQLGLN PLPETVSKHP EALDDVKIIL KSCKFDELVS SKKE
//
