ID D7EIE4_TRICA Unreviewed; 2314 AA.
AC D7EIE4;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 2.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=PHD-type domain-containing protein {ECO:0000259|PROSITE:PS50016};
GN Name=AUGUSTUS-3.0.2_04063 {ECO:0000313|EMBL:EFA11906.2};
GN ORFNames=TcasGA2_TC004063 {ECO:0000313|EMBL:EFA11906.2};
OS Tribolium castaneum (Red flour beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrionidae incertae sedis; Tribolium.
OX NCBI_TaxID=7070 {ECO:0000313|EMBL:EFA11906.2, ECO:0000313|Proteomes:UP000007266};
RN [1] {ECO:0000313|EMBL:EFA11906.2, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:EFA11906.2,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=18362917; DOI=10.1038/nature06784;
RG Tribolium Genome Sequencing Consortium;
RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R.,
RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M.,
RA Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S.,
RA Schroder R., Tautz D., Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M.,
RA Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D.,
RA Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H.,
RA Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A.,
RA Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V.,
RA Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J.,
RA Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S.,
RA Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B.,
RA Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R.,
RA Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L.,
RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y.,
RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G.,
RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J.,
RA Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V.,
RA Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S.,
RA Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B.,
RA Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W.,
RA Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V.,
RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M.,
RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M.,
RA Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D.,
RA Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E.,
RA Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M.,
RA Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N.,
RA Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C.,
RA Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H.,
RA Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M.,
RA Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R.,
RA Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J.,
RA Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B.,
RA Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C.,
RA Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B.,
RA Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H.,
RA Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y.,
RA Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P.,
RA Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S.,
RA Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W.,
RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.;
RT "The genome of the model beetle and pest Tribolium castaneum.";
RL Nature 452:949-955(2008).
RN [2] {ECO:0000313|EMBL:EFA11906.2, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:EFA11906.2,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=19820115; DOI=10.1093/nar/gkp807;
RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W.,
RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.;
RT "BeetleBase in 2010: revisions to provide comprehensive genomic information
RT for Tribolium castaneum.";
RL Nucleic Acids Res. 38:D437-D442(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ972879; EFA11906.2; -; Genomic_DNA.
DR RefSeq; XP_968788.2; XM_963695.4.
DR STRING; 7070.D7EIE4; -.
DR EnsemblMetazoa; TC004063_001; TC004063_001; TC004063.
DR GeneID; 657224; -.
DR KEGG; tca:657224; -.
DR eggNOG; ENOG502QW8S; Eukaryota.
DR HOGENOM; CLU_230113_0_0_1; -.
DR InParanoid; D7EIE4; -.
DR OMA; ACNKGYH; -.
DR OrthoDB; 5490909at2759; -.
DR Proteomes; UP000007266; Unassembled WGS sequence.
DR GO; GO:0031213; C:RSF complex; IBA:GO_Central.
DR GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd15543; PHD_RSF1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR028938; Rsf1-like.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR14296; REMODELING AND SPACING FACTOR 1; 1.
DR PANTHER; PTHR14296:SF3; REMODELING AND SPACING FACTOR 1; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007266};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 1457..1507
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 192..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 577..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 877..1448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1558..1629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1669..1918
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2114..2233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2263..2314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1972..2006
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 192..206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..279
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..321
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..343
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..562
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 877..1120
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1121..1146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1185..1199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1201..1283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1313..1336
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1345..1361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1400..1419
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1420..1448
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1565..1599
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1600..1629
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1684..1707
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1725..1753
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1754..1785
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1792..1820
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1821..1840
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1841..1918
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2135..2150
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2190..2214
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2314 AA; 263253 MW; 41AA2699048C6875 CRC64;
MASDNEATCE SDPNFAVICA FMEKFGTTCG LQSIDFLLLQ EMLENTQEVP QELIDLHIKL
LRKSRKSVSN ERWERAIIKF CHTFCSQDAW EIERFGYKKA RLSSKIRVLK ELLEMQFDYN
TRFKAEINKM SAEELRSQPL GKDKQGHAYW YQDDINCQIR VYKEDPDEET WTLVAKDREG
LVALMNELSD GDSKISSESA INEEDSNSLA EKPIIDTGQV DSSSSESKKL SGDSENSNES
KENISQEEEE EEESAKRRRE SDEENGEAKK AKLGESPIVG EEIEEEVMIF AGEGSGRECE
TGNEEKPSTS DKKDAKSDSD FVSINDSKNC VKNSPPQQYK LGTIIDTKTD NKFFNTVRSP
TKKSRWDVET IIAKVEETPP KKPMFFFGPG CLQFKPAATV GFGQKVPQEK KNEDLDVLPT
NAKGDIGYRI ENEDTTPKHD NEDTVEPVPV VEETCIKKHA YICGEEEDTK VEDEKKSNVL
ITEDEENKLV EESNKEIEKP KENDPIIEEP KPLNEEIVKT VEEEEIKSEE SVKIVEQTNV
RNEESVKTSE EEETKSIGEE PKLLNEEIIK TVEKDEIISA GGEESPVPKE ESLKRTKIEN
EESVIVTELS EQKREDICTT PHDEEIIEAK SSELDKDTNQ RTEQIIEESV VKEIIDTKPS
TVDEETINQL TEESLVKPQS EEIIAKPPKI DKEESLIEET DKKIIEESAN KPKCEEIFEA
KPIKVDEESM VKAEMTEVGD DKVLKNEDSK IEEKLESKTV NSEETNEEKI GVILENVKND
GKAVLNEEVL KKEKVPMVEK PSEPVLKDEI SSVVEEPSKQ TEEKVAVVEL LKSELKEENS
SVIEETPKPA LKEVNASLVE EPQRSELKEE KVLVVEETKP ELKEESASIV EELPKTELKE
ENSLIIDDKA QKPELKEESP SVVEETPKQK EEIVSLVEEP KKELKEEKPS VAEEPLKQKE
EKVPLVEEPH KSESNDENMV EALKPPESKE ENTSVIEEPP KQEAKEKNTL VEESEKPEIA
VENASKLELK EEQNEEKEQK ANNKRGRKNN SSEATPEDEK KPRITRRSTR SSKNGEKQSE
TIEEIQAPTR RGRPRLSQKD ENGKKMKMSE EIREESEDLK QASAASSPIA PETVIVESSN
SSDIVEIQDK DPLAEEKPEE TEEKSEETEE KPEETKEKPM SLANFSLDFT ESTESPPVTR
SGLRKRGRES PQNAEEIEET SGKRMKMKAK RAVDVKLRKS IEEQKKAELV SSDDDNKNEE
KMKKPPKKSD EETKKEKTKN KNKRLLSNLG IDPERALEIE ENQTIGVRQS RRIAQLKIKE
EAERRKLEEE MVHETHKKKK SKKHEDKDYK VEKKKLKNEV DDEDQEEDSA DSKKKKKKKK
KHRKLFDEFN PWRSSSDSSS SEEEEEEEIA EEEEEELQYV SDHEFSPESD LEGDGEAQPL
KRARTARKES DVEEVDDCPC QKCGKSDHPE WILLCDSCDN GWHCSCLRPP LLVIPEGDWF
CPPCQHASLI SKLQEKLKEY DKKLNKKEIE DRRKQRLAYV GISLNSVLPT KDTENIKKRR
LSIEDEEEED DEDDDEEEEN DEDAEVGDEE DENSSSEESE SGETESRTGS ESDEPIYQLR
QRRQAHSYRF NDYDELINSA IQDEMEAVKG AGNQGRGKDI ATIVNAEKEE MKNEEIEPLP
PVVPVNDKDR DAKPVFSEDE AIQSSRKRII GRKKHRKLNS LDISSEDEDS DEDFKGTSSE
SDDDFDEDLG SEDSEDLSTA RNRRRGEVIR RSTRARTSRY DADFIDDGDS ESEEEAPRRK
KKRSIWEESE SEESDRSWGR RRKKPAKKTT TSSTTKKKSK KKKKEDSDVE VYKKKKPKIK
FNDEGPGRRT RGKKINYVDA LGSDSDEDRV KRPPPRIESE EEYVASEASD DEETVKKSEK
VQIQSYTDAR FTQILPEPKN ILQEDGETEL NPIDQINRNV EMMDENQMEK MMEEEEYANK
QLQLVAQQLE KEKRRKEREA KKEFLQEPLV GNVIVNSENN DELSEPPGVS LPLFADLGED
EAKKRRQGKN KKSLEETVAN LGKESNIEIA APPQPFSQSQ PTPSVITRML QSKPGQPGYP
IGAIRPKQFA AMPEDDPHFA QGVRPQLSTP YRFNHYPPRN PPPPLRAPLP PQLYHAHRPL
DPSPSGGGTI TMSDHSPARV VSPAAGSPGN KTETPPPPYS RPPVPPPVGR FPPRHMQMVP
PHLQTTRPNL SPYHPPAYHY GQFGGQEDAA TATAPAPPTL GVYQNAPYPP ETTFEGVNHP
GENSNSKTFD EEGGGEFGGL VSYFSSQRED DLES
//
