ID D7FIW7_ECTSI Unreviewed; 1694 AA.
AC D7FIW7;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 03-MAY-2023, entry version 43.
DE RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
GN ORFNames=Esi_0124_0012 {ECO:0000313|EMBL:CBJ28915.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ28915.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ28915.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF1 family.
CC {ECO:0000256|ARBA:ARBA00009064}.
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DR EMBL; FN647898; CBJ28915.1; -; Genomic_DNA.
DR STRING; 2880.D7FIW7; -.
DR EnsemblProtists; CBJ28915; CBJ28915; Esi_0124_0012.
DR eggNOG; KOG0008; Eukaryota.
DR InParanoid; D7FIW7; -.
DR OMA; YMSFHIL; -.
DR OrthoDB; 5482320at2759; -.
DR Proteomes; UP000002630; Chromosome LG34.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:InterPro.
DR GO; GO:0001091; F:RNA polymerase II general transcription initiation factor binding; IEA:InterPro.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR040240; TAF1.
DR InterPro; IPR022591; TAF1_HAT_dom.
DR PANTHER; PTHR13900; TRANSCRIPTION INITIATION FACTOR TFIID; 1.
DR PANTHER; PTHR13900:SF0; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF12157; DUF3591; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 3: Inferred from homology;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630}.
FT DOMAIN 1553..1622
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 295..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 710..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1204..1331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1491..1515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..265
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..364
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 710..739
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1210..1226
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1249..1301
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1501..1515
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1694 AA; 180956 MW; 607F8105262A2A43 CRC64;
MHTNKDNTEG GAGAGARPSS VAQEVGKAAR QGQAGRVGGI LMWGRSELPN GLEGEHFFPD
VVPKVDPVDF HDAGEEESGN YDLVEDLVTE ETYKPEARHM AATAASEADK SGDGVGGNGA
ARPRLGGASG RANGTSGSGD AAPQHGGGVV GADSASGGVA GASVQANGGT SGASAERIRA
GENDMDVDEE EEGGSVAEKG KGPARRPAAA RGVDARQSQR ESEGKGLAGE VDSDDDEESS
GSEPERGSSS DGDGKGGEDG RGGGDDGLDG PGAVQLLGLK AEFMPVSQGA WEDAVCLGDS
GESDAESRRR SPVGGRSRSS PVPTPMDVSA SGCDEEREEG VGAAATSKKK EEGRGRDRTV
EDGARGAAEG ISGSKKPAAV AASAAGAAAS GSKKVARRRA ATGMGMRTTA FPAAEGSPWI
DPPSVLNPQV DGGGWESQVL LDDSQKLKKP TIPVYLDDPD MLFGALHTPR PSLRILQTEA
QQENSHILER TNRRQMATEK QKRLQSAAMK TGYTINTVGD GKASRAESNI RAVIIRPPHH
ASPAEDKVLI AAPKSWEDIR NLHRPRMQIH TLLPNQMSIV RLPRKPKALQ GGGQGGGGFG
ARIGEVVSMP MHREKDLLPL ESHSTFVVVE YVEERPPLLG STGMASTIIT FVRSSSRRPI
GGIERRELSP QEDSPFLGEI RPGSEQASIC NGLFRAPIFK HHAPDSDFLL IREPMTKSEK
ERSSQKQKSK KEKSGKFFFR GDKGGGGSGG SGGGGKNAPG GGAAGSSSSS SSKATFRHNQ
FYVIRPMPVV FLVGQTEPQM EALEPTKATS KATHLNIVTF LAKRLFDTTK AAQAGNAGIP
FKKVLEEARF LSLPRAKDSA KGRLKEMVRE IGERRDARDD GDGPVSTESL WAAKPDLNMQ
QVTAQAAKLF RPEDFCALES MVSAWAHLSD VGLDTLTSHD AVAKFLLKIK KRHDCLLAQV
KEVRSASSAL SKQKSVLARA ARVRGRQPPE HDGGLTRRLA CMEKLSEILG TQLTELKRVR
AVAQYMYKEL QMVPWTLTIN YLKRHGITSS PAASLLMLSG MGDPSGCGEG FSFLPRPAEQ
AKATASLTTS QKIVAERSVQ KVTGTNSDLR RLTMLQLAST CEAMGIPKDT VKTLRRWDRV
HMIKELAGVA VAENVKDQNI YARFVRKRRP NATIDKDLYR ATCNEIWERQ ALALSATAED
VQEYGSESAS SSKAKDKVEA SKGKGGEASK GKAAGASPGG SKDSDKGEEK EDGDDDKEDD
DDDDDDLDGL NVDDLDLSGD DDDENDGLNL SDMEETLEGG DGDGDAPVAK SLQDLSSSSQ
KNTDELDDER QYRMLQQDLH GVRGEAARWG TGEGSDAAPQ GSMSLNVVEA RKAQTEELLG
QLGGRAQLPA QAVRRITRTV GPDGTETVRV SYSLRRQDLV RLDARGGKKQ TALSKSAAAS
GGVGGASPLS FFLPRPQASA ESKAAAYEER GAAAGQEETV LKIRLKTGGL TTVAPKENKK
KRRRSSTEGR VRKPEENIYA IQRQNSRSTV ESRDSRPRNR MRSLLTGVVK NLSERPDSIY
FRAPVKRNVP DYYTKIKKPM DLRTIQDKIN NFDYTSRENL IADMLQLVTN AEIYNGHGHV
LAQNARDIMA DCQAQLEDPE IAEVEESLTA EHPVAMRNPP SAIPESTCMA SKFHQDVCLG
PVFGAQCLSG DISA
//
