ID D7FNN8_ECTSI Unreviewed; 1438 AA.
AC D7FNN8;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 22-FEB-2023, entry version 44.
DE SubName: Full=Fanconi anemia, complementation group I {ECO:0000313|EMBL:CBJ26049.1};
GN ORFNames=Esi_0018_0144 {ECO:0000313|EMBL:CBJ26049.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ26049.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ26049.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
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DR EMBL; FN648291; CBJ26049.1; -; Genomic_DNA.
DR STRING; 2880.D7FNN8; -.
DR EnsemblProtists; CBJ26049; CBJ26049; Esi_0018_0144.
DR eggNOG; KOG4553; Eukaryota.
DR InParanoid; D7FNN8; -.
DR OrthoDB; 1210920at2759; -.
DR Proteomes; UP000002630; Chromosome LG02.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR InterPro; IPR026171; FANCI.
DR InterPro; IPR029310; FANCI_HD1.
DR InterPro; IPR029308; FANCI_S1.
DR InterPro; IPR029315; FANCI_S2.
DR PANTHER; PTHR21818; BC025462 PROTEIN; 1.
DR PANTHER; PTHR21818:SF0; FANCONI ANEMIA GROUP I PROTEIN; 1.
DR Pfam; PF14679; FANCI_HD1; 1.
DR Pfam; PF14675; FANCI_S1; 1.
DR Pfam; PF14676; FANCI_S2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002630}.
FT DOMAIN 98..372
FT /note="FANCI solenoid 1"
FT /evidence="ECO:0000259|Pfam:PF14675"
FT DOMAIN 392..444
FT /note="FANCI helical"
FT /evidence="ECO:0000259|Pfam:PF14679"
FT DOMAIN 524..692
FT /note="FANCI solenoid 2"
FT /evidence="ECO:0000259|Pfam:PF14676"
FT REGION 454..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 795..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 962..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1036..1062
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1169..1196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 962..989
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1040..1062
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1438 AA; 148892 MW; E8A16FAC4A34A847 CRC64;
MDEAEATWER FVSCKSLLTQ FQNFQTSQQG GGFGGILSSS SSNANSETST LIRELTVRPV
SKLLSDEAVQ GLAKQDRLVD FIQLVLRSRS RNTPGTAARV QEIAVVGIKA IHSGLVVDKP
AQELQNVLLA ELGDISPDHA PAIVNAVLAP LLEASKCQGR LTVGHQRQSS EREMSEEAAA
SFLVVLDILP KVLSVTAGVP TLSEEDPVPE DVRGLSGAQY KDRVVSCLFR ARWPGAVSVG
MCQTLRDLDL GERHLSVAVS RVLRHLRKNA KLHDLPALTY QLLLLAGRGC KEAALEGVIQ
VFNRLDAEAA DREDAAAGAA GGIPIRPISG GRGGGGGGSI GRGGGGGLGT NSTEELRFVE
GTILLHFNFA MKQDHSLASC VLKGFQRRAA AAEVGRAFTP FRLALLLSLA RIQRFQQPVL
DLVEEIVSDC LVYDHLREGS AWLESEEEAA RGGRRWQRYG GGGGGGGGGG RAEGRDGGGG
GASDGEDGVS GGGGGGGGSS SSAKAVERVL LTVVAFSRGW DHLVDSLLRL GLRLLDRGGG
GSSSPGAVGA SRGMLEKLQG AQSHRAALRA SYLGRVVLME TFKTHEVVRD QVLSAVLEQV
TARSQGVLGY VKLLGLLVQR YPNLLLGKAA AVQDVFGYIS VLPPTVAERF LQAVSPLMRL
RPGLQDSVVL PLRKALFSRE ERARLVAVGG LVLLLKDQSR NAAAVAGRGG LSGGSNGGTQ
MSQTSQMSEG QQMAMVLPFP LAAGGGSGGG GGSALSLAEG FGLLRRCLTQ QMVVRAKLYD
GLLSCFVQGE SLAEHARSSS SSPSRGGGAV DPENMLDDDD GDGPLVPADA AAAAAAGGLR
ETLNELEGDL RRLSTALSGC PLSEFDLDKV ADFSPSGGLA ARTKLATAAL LCGSYEALMQ
GSLLLPATVG GQRSAAAAAA AVSPVHGCSK LPALASVQGV LRLFDCRQAL LDLVTPSLPT
AAQQRAKKGN GGAVSNSNSS SNSLWGESES ASGGGGGQPG FSAAGCFGLT LYPGGMPCLG
LAFVEDMLAV LNVDASGGEE TEGDTERDPG QMDVDLSRDD PPTEAVREDL GLQRLALETC
RGHLRCLRAG AAQPSSGGGG LEVDVGGGPS AKGVAGGVHG GGPRDEADAG RAGKAAVKRC
AVLAPLLLKE FFRQVTTGNT SGAARDAAAA AKASKGKGKS GGGGDKGTKK KTPSAPSESL
AELALSCFEE CVCIAAHCSP QKGTAASRTA KMLAAAYDSF PNSNVAPADP AAGRGGSGGG
GGAAVAAGVL GRHAEGLVNT FVSLVGDDQM KEAETVCRIL SQLTRLLRLH PKSLETHGAS
LKRVCEQQNI KCPSLAKAVI SLYLEAHMSM KAKGGRIAAL HDVARQVSAC LGPREEDDEE
DDEPPVVTFQ VINNFTMNAI NDVPNPKVYL SSRRLPSERC RRASATWNTR CACCRRRP
//
