ID D7FRQ7_ECTSI Unreviewed; 1161 AA.
AC D7FRQ7;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CBJ30848.1};
GN ORFNames=Esi_0217_0029 {ECO:0000313|EMBL:CBJ30848.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ30848.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ30848.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FN648395; CBJ30848.1; -; Genomic_DNA.
DR AlphaFoldDB; D7FRQ7; -.
DR STRING; 2880.D7FRQ7; -.
DR EnsemblProtists; CBJ30848; CBJ30848; Esi_0217_0029.
DR eggNOG; KOG1420; Eukaryota.
DR InParanoid; D7FRQ7; -.
DR OrthoDB; 51137at2759; -.
DR Proteomes; UP000002630; Unplaced LGUn.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF10; SLOWPOKE 2, ISOFORM D; 1.
DR Pfam; PF03493; BK_channel_a; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR PRINTS; PR00169; KCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 219..285
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 442..545
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT REGION 641..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 788..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 852..920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1007..1026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1137..1161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 856..904
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1161 AA; 125889 MW; ACBC1FA761DA0F82 CRC64;
MGGAASETPV TLSAAGSFLV FFCYFSYVLF SVPRHGEVPY TNRLNRHITT SRCGLFIEIL
NALFSLATCV LFVLETYSFG NNYGFIVMSF SMEMVFNGFF LFNFLLHLYL AVDKLTHLVS
LQAVVDIVTV FPSYLILFMN DGWRTSDGGF ADAYLGLKIT RVIRVARLLV TISFFVQGPS
LAFDHSRQLL VLRSQLVRWS LKTVLVIFTM AGLTNFLVVV QDADWGLGYG RMPFHEALYF
VVVSFSTVGY GDISPSTALS RVVITGLILT LFFCVPLVTN ALVNLTKLTP KHGGCLSKSW
GTGHIVVGCD ASCLRVVSVL LRDLLAADSM AYHHEHVVLV IPQEPTLAWD ALLCLQPSFA
VTYLNGDLSS AKDLRRARVA NARACFVLSD RLANDTEAQD KTALLRALST NQASPPGSSV
LCLVTHSRSK GRLVRLGMPE ASVVCYDEVM EGLVTQACLN PGFSTVWTNM LSCMPEADYL
LKTRGAEQDV TRDPESTALF ETETEYLRSL RRVTLRFRLT CFAGECTGDA AIELHEKCGC
ILFALICNIC SGGHKSRVKC GAGKRRRRCV RVHPDYGTII SKDDVGVFIS ANHESADLLA
RYCTGRATSG AAATAAPSKA SGTSLRREGW VENAFLVAEN PPVGNRQHGT QENRQRNASS
GDGRFERTIW SDVHDAGGGA STPSVFPLGE SLVGTPPGAV LVIAQSLSFA LGVVLSLCEA
DDDLDVEGSP ALSVVCSPTW WDPVADERAE RELAARFPCV RLVKRETEYE CLLEVGADKA
DLVCVVSSRP EDEPTTPKTG GGGGDGDVLG DHSGRGQGSD VWAMGVVVDV LGLVPESTRV
VVRFDDSASA EQHQVISAHV RRREDAQETG RRERAAAESG EKQGEENLFD GRKEQTDRAT
QQQRDAPRNE NAGTTVEDSV DFGYSARSGV GGGGVYFDDT RGVVREGFDD FFGTMSGYVS
GDVVVGNAAE LLLLQTMLAP DIQSLMSDVM HLVSRVPIEV LWPEHSPNAR GTAVGDNNDN
RGDGDIRRSR IRPVTYGEAF RLLLEDRDLL ALGLHRPPTH GRGPRKMGGR ERWRCPGGSR
YVAINSPSAS FALRDGDCFF VLRRRSRPVS AFNSEPAVDP LVTGTCVSSG GRATAALAAT
AADPTEGTTT PGKDTPERLH G
//
