ID D7FTB5_ECTSI Unreviewed; 391 AA.
AC D7FTB5;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Inositol 2-dehydrogenase {ECO:0000313|EMBL:CBJ31381.1};
GN ORFNames=Esi_0249_0030 {ECO:0000313|EMBL:CBJ31381.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ31381.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ31381.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
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DR EMBL; FN648430; CBJ31381.1; -; Genomic_DNA.
DR AlphaFoldDB; D7FTB5; -.
DR STRING; 2880.D7FTB5; -.
DR EnsemblProtists; CBJ31381; CBJ31381; Esi_0249_0030.
DR eggNOG; KOG2741; Eukaryota.
DR InParanoid; D7FTB5; -.
DR OrthoDB; 1992171at2759; -.
DR Proteomes; UP000002630; Unplaced LGUn.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR030827; Myo_inos_IolG.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR04380; myo_inos_iolG; 1.
DR PANTHER; PTHR42840; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR42840:SF15; OXIDOREDUCTASE; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..391
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003095875"
FT DOMAIN 52..171
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 184..382
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
SQ SEQUENCE 391 AA; 42099 MW; F9826C6E8E0606B2 CRC64;
MMQSGAMLAL MATCSSCSAF VLPQASFNRL PTAASSASRA ASPLRMAEEP LGVGVIGCGR
IGDIHAKTLA FRTPGAKLVA VSDIFEEAGA RVVEGCNGLP KFYKDWKEMV HDPEVGAIVV
GSPTPFHAEQ IIEAAKLGKH IFCEKPISFD VPTIDVALKA VADNDVKLLL GFQRRFDSNF
RTIREKINEG TIGDVRTIHI TSRDPAPPPV AYLQNSGGIF MDMTSHDFDM ARFLVGDEID
EVFVTATAFD PEAKEADDFD TANTHLKFKN GAFGVIENSR RCSFGYDQRV EVFGAGGSIS
GANRSPQNVL VNNEDGLNAG VPYSFFLDRY ADSYVNIMSA FVKYVKTGDE SLEPALGIDG
KVTIFIGMAA ARSAKEGRPV KISEIAAEFG C
//
