ID D7FU18_ECTSI Unreviewed; 1755 AA.
AC D7FU18;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Phospholipid-transporting ATPase, putative {ECO:0000313|EMBL:CBJ31545.1};
GN ORFNames=Esi_0263_0021 {ECO:0000313|EMBL:CBJ31545.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ31545.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ31545.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FN648446; CBJ31545.1; -; Genomic_DNA.
DR STRING; 2880.D7FU18; -.
DR EnsemblProtists; CBJ31545; CBJ31545; Esi_0263_0021.
DR eggNOG; KOG0206; Eukaryota.
DR InParanoid; D7FU18; -.
DR OrthoDB; 103847at2759; -.
DR Proteomes; UP000002630; Unplaced LGUn.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016459; C:myosin complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 2.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 2.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032631; P-type_ATPase_N.
DR InterPro; IPR032630; P_typ_ATPase_c.
DR PANTHER; PTHR24092:SF214; PHOSPHOLIPID-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR24092; PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF16212; PhoLip_ATPase_C; 1.
DR Pfam; PF16209; PhoLip_ATPase_N; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 259..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1187..1205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1226..1246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1261..1279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1309..1330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1342..1360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1372..1396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1402..1428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..59
FT /note="P-type ATPase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16209"
FT DOMAIN 1098..1151
FT /note="Myosin motor"
FT /evidence="ECO:0000259|Pfam:PF00063"
FT DOMAIN 1195..1443
FT /note="P-type ATPase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16212"
FT REGION 475..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 701..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 744..768
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 799..824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 977..1012
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1508..1530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1557..1596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1611..1635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1657..1704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 859..893
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 478..504
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..549
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1516..1530
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1664..1685
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1755 AA; 192641 MW; 0F50C73A75936A32 CRC64;
MLDMRYLHAF AGYTHWDFLP RFLMEEFHPR RKMANAYFLV LASLQTIPEI TNTFRVPTIL
LPLSVVVIVD AVFAILEDVG RHPANPKGNA SPTRALDVDL QRSAGKFPRV EWRDVQVMGA
HEPNPQAKAG ICYVETKSLD GETNLKIRQA IRSTIGRVST PRDAAALKGR VVMEHPNKLI
DNFSGTIEVE GAGDDGGSCR EVIQTRNLLL RGCVLRNTRW VVGLVLNTGP DTKIVMSSLE
PPHKTSRLEQ RTNVEVWRIV RLLCLVCFLG AVGSLVWNAT SAEDHVYLRI DVGSWGNQMK
TTFIQFLYLF LLLGNFIPVS LYVSMGTVKF SQAFFMKQDL DMYHEDTDTP ALVRTMALNE
ELGQVSHVFS DKTGTLTQNV MDFRKFSVGG VSYGRGVTTI ARAVAAELGH EIPQEDLEAE
AVIAKQPPVP HVRFYDPRLL EDLQSSTGEE QRALLLDFFL ALAVCHTVIP ERGLSSRSGR
RRRCRGPGGG SRHPHRSRSR ERRRTNKPVG REQSRQTRYS SGARTGDFVQ DGEEEEEEEV
VAEQREQEEQ EEEGPAKLSA SSPDDEALVL GARHFGMEFR DRLDNKACVR RSGPFLRGQQ
QHHQQHPLRS PPAPGEKPKG EEGRDGRGFA TGGEGGWPQV AEQGSRPGGD RFVDEKYEVL
RILDFTSARK RMSVIVRAPD GRVRILCKGA DSVMIPRLAR NSSASDSSAG DSVPDDHHHH
LDASNPLPFG AAFGPAATAI PAPTTVAPAP APGGKTLPAA SPQEGAAQAV SPASDAAVNA
AAAVRLPLAD VVAEECGGGG GGLAGNWSTS SEDNRPGGER SEERTLKHME TYAREGLRTL
LVTCADLDGD WFRAWDKRFE TASTDLSEVE KKKQGLENEI DRLMNEVEKN LRLLGCTAIE
DKLQDGVGTC VDALQRARVK VWMLTGDKEE TAINIGVACQ LLGPEEQMER IIVNMDPQTG
CQDVEEVKDR LEDELNRISD EDPFHKSRGK GSGGTGDGGT GEDGGGVPRK GGRQRALIID
GQALSLAMDP ACSKYFAELA MECEAVVCCR VSPDQKRAVV ALVRERRPEA RTLAIGDGAN
DVAMIQAAHI GVGISGQEGM QSVGAQFKNQ LNSLLGAIGE THPHYVRCLK PNDENVRSQF
DLGRITAQLA NGAVAAKARR EAALRDKRCR QRGGGIYGRH RPVCCRTLLY VPLAVNASDF
AIAQFRFLQK LMLFHGRQNY RRMSKLVAYT FYKNILMAVP MAWYMVVNGY SGQKFYTEGG
IQFYNIMFTL WPILFLGCFD RDVSLKDTEN FPQLYVLGIN DVFFNAKVFW SWMSQAIVEA
ALITFVPLLL LKGGPADDGA EVSYMFYGGT TFSLVVLLAN SKILWLQYRW TWWAAVLVMA
SVLAWFGTAC VLNILHKVDF DFFMVFFHLM VNPTFWAVVT LCFTAVAMRD LSWKFYHRWW
QPKLHHLILE VEASRGDPVI LTDSGTPEVG GGGAGFGVGV ADSRRKSWER RGKRAGDGLG
GRAVAVQGEG GATAAGRDDD GFEKQARRED KASAVLSPAF SDAVELCLGG EDAGDAVAER
PRGGREEVLG GRAGASYGGG GGGGGRGFRR GHSHDDDEGY AAVYRRLTDA LSSQPSTGNG
GGEGTSVTPA TSHCPSVSST LPLELIFPAV AAQGPVAMGR SRSDQLPKRS SSSRRLQQSP
HQSGAVGTRF PRAPSGGFAY STDEDSASME SRMILNYVES PLKKTPEFWE APRPVLDRLN
RRRERGKFCW RWCRC
//
