ID D7FX60_ECTSI Unreviewed; 516 AA.
AC D7FX60;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=WD40 repeat-containing protein SMU1 {ECO:0000256|ARBA:ARBA00026184};
GN ORFNames=Esi_0032_0119 {ECO:0000313|EMBL:CBJ26393.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ26393.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ26393.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
CC -!- SIMILARITY: Belongs to the WD repeat SMU1 family.
CC {ECO:0000256|ARBA:ARBA00025801}.
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DR EMBL; FN648509; CBJ26393.1; -; Genomic_DNA.
DR AlphaFoldDB; D7FX60; -.
DR STRING; 2880.D7FX60; -.
DR EnsemblProtists; CBJ26393; CBJ26393; Esi_0032_0119.
DR eggNOG; KOG0275; Eukaryota.
DR InParanoid; D7FX60; -.
DR OMA; MMKQQEP; -.
DR OrthoDB; 3893433at2759; -.
DR Proteomes; UP000002630; Chromosome LG04.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR045184; SMU1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22848; WD40 REPEAT PROTEIN; 1.
DR PANTHER; PTHR22848:SF0; WD40 REPEAT-CONTAINING PROTEIN SMU1; 1.
DR Pfam; PF17814; LisH_TPL; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00667; LisH; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50896; LISH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 224..247
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 262..303
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 305..346
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 347..388
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 483..516
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 516 AA; 57512 MW; 8990DA1926E8D775 CRC64;
MSFEVESEDV IRLILQFLKE NNLTKTLRAL QAESSVCLNT IDNLDNLMSD INHGRWEAVM
PQVSSLSLPL AKLVAVYEQL VLELLEMREL DVAREILRTA DPFLQMKKEE PDRYLRLEHW
LQKGAAIDPR DLYPAGSSKE KRRAEIANML IPEVSVVPPS RLLALVNQAL KWQQVQGLLP
RGQKFDLFRG GARASKKDME EKPPRKMAGQ IKFGTKSHPE VARFSPDGQY LASGSVDGFV
EVWDFDTCRL RKDLAYQAKD EFMMHDKAVL CSSFSRDGEH LATGSTDGKM KVWKVSTGQC
LRRFESAHTQ GVTSVAFARD GSQLLSSSMD QTARIHGLKS GKMLKEFRGH TSYVNTAVYM
HDGAKVVTGS ADGTVKVWDA KTTENLHTFH PALSIGSHTE ASVHTVRPLP GSAEQVLVSN
RTSTAFLCTL QGQVVRSFTS PKSVRADFTC ACLSPKGRWV YCAGEDGELF CFDAATTEVE
KTLKVSEKEI IGLAHHPHRN LLATFSNEGL LKLWKS
//
