ID D7GY22_TRICA Unreviewed; 1083 AA.
AC D7GY22;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE SubName: Full=von Willebrand factor A domain-containing protein 8-like Protein {ECO:0000313|EMBL:EFA13666.1};
GN Name=AUGUSTUS-3.0.2_04261 {ECO:0000313|EMBL:EFA13666.1};
GN ORFNames=TcasGA2_TC004261 {ECO:0000313|EMBL:EFA13666.1};
OS Tribolium castaneum (Red flour beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrionidae incertae sedis; Tribolium.
OX NCBI_TaxID=7070 {ECO:0000313|EMBL:EFA13666.1, ECO:0000313|Proteomes:UP000007266};
RN [1] {ECO:0000313|EMBL:EFA13666.1, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:EFA13666.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=18362917; DOI=10.1038/nature06784;
RG Tribolium Genome Sequencing Consortium;
RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R.,
RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M.,
RA Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S.,
RA Schroder R., Tautz D., Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M.,
RA Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D.,
RA Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H.,
RA Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A.,
RA Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V.,
RA Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J.,
RA Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S.,
RA Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B.,
RA Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R.,
RA Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L.,
RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y.,
RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G.,
RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J.,
RA Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V.,
RA Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S.,
RA Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B.,
RA Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W.,
RA Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V.,
RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M.,
RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M.,
RA Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D.,
RA Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E.,
RA Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M.,
RA Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N.,
RA Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C.,
RA Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H.,
RA Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M.,
RA Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R.,
RA Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J.,
RA Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B.,
RA Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C.,
RA Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B.,
RA Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H.,
RA Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y.,
RA Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P.,
RA Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S.,
RA Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W.,
RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.;
RT "The genome of the model beetle and pest Tribolium castaneum.";
RL Nature 452:949-955(2008).
RN [2] {ECO:0000313|EMBL:EFA13666.1, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:EFA13666.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=19820115; DOI=10.1093/nar/gkp807;
RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W.,
RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.;
RT "BeetleBase in 2010: revisions to provide comprehensive genomic information
RT for Tribolium castaneum.";
RL Nucleic Acids Res. 38:D437-D442(2010).
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DR EMBL; KQ973033; EFA13666.1; -; Genomic_DNA.
DR RefSeq; XP_975275.1; XM_970182.3.
DR AlphaFoldDB; D7GY22; -.
DR STRING; 7070.D7GY22; -.
DR EnsemblMetazoa; TC004261_001; TC004261_001; TC004261.
DR GeneID; 664169; -.
DR KEGG; tca:664169; -.
DR eggNOG; KOG1808; Eukaryota.
DR HOGENOM; CLU_001400_1_0_1; -.
DR InParanoid; D7GY22; -.
DR OMA; KGHDIKQ; -.
DR OrthoDB; 37271at2759; -.
DR PhylomeDB; D7GY22; -.
DR Proteomes; UP000007266; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039891; VWA8.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR21610; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR21610:SF9; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR Pfam; PF07728; AAA_5; 2.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007266}.
FT DOMAIN 893..1075
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 724..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 727..741
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1083 AA; 121030 MW; 60342F191A5B41D9 CRC64;
MKAAAPTAPD STITKLLSCA FAISSKESAA LGFPDFPLDN LTLGAKILEN NPKLPPYDLF
FRLYPYKLFL KEQTTHLESL LESFDVKPQP QSVFSAFTQK VKTFLATPTP KKTYIETDYQ
NKLIEEMLQS EQTADFCIIG PRGSGKSLLV QQVANIAGKQ TENIVLYQDM TARDLIQQRT
TLENGDTVWT LSPLVLAALE GKIAVLDGIH RIHPSTLSCL HRLVQNRELQ LHDGKRLISH
ERYQLLKTKT TPTDGVLPIH PDFRIVAIGE PPNTNTTNWL TPEVLSLFLF HEVRSLTKQE
ELHVVTSKYG PVSPQMHKII ELAHVLRHSG DQTLLNLAGH LSTRQILRLA ARMSQFPTTD
LYDVLETTFM VKFLPSLARG ALERTFERLG VTQAARDPIS VKCEVQDGVL TIGASSVPVH
QTSNLSKVPE ILFYDVPQHL QLMERLLQDF HLGQHILLVG NQGVGKNKII DRFLQLMNRP
REYIQLHRDT TVQTLTVQPT VKDGVLVHED SPLVKAVKSG HVLVVDEADK APTHVTCILK
TLIESGQMVL SDGRRIGGTS PHHIPIHPDF RVVVLANRPG FPFLGNDFFG ALGDLFSSHS
VENPEPEAEI ALLRQYGPEV PLETIKKLVK VFGELRNMAD QGLVSYPYST REVVNIVKHL
NQFPNSDLEE VIFNVFDFDR YSSEVVDTLG EILEKHGFTG GKNLMLTPKK VKERIQVTVN
RKSGLDVSAP KHGKEDPKNE PHVGGNTWAG GTGGRDTAGL GGKGGPYRLD KGHKVHQLSD
EEKNSVPEHV QRAAREMGRK AFQEKLKEIG MSGYDASLYN QFYHSVERQV QSLRVILGNL
QAKNKERHWT RHQTAGELDD VKLIDGLLGE KTIFRRRAEQ EPELGAPQIK PKLFRLVVDV
SGSMYRFNGY DGRLDRELEA AVLVMEAFQG FDDKIQYDII GHSGEAPSIP FVKFKEPPKN
NKERLDIIRT MHAHAQYCWS GDHTLEGAES AINSLAEEDC DEGIVIVLSD ANLERYRIPP
SKLAQVLTSK PNISAYAIFI GGLGDQAERL TEKLPAGRAF ICRDVTQLPQ ILKQIFSSSV
INI
//
