ID D7L1P1_ARALL Unreviewed; 838 AA.
AC D7L1P1;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 22-FEB-2023, entry version 75.
DE RecName: Full=Lipoxygenase {ECO:0000256|RuleBase:RU003975};
DE EC=1.13.11.- {ECO:0000256|RuleBase:RU003975};
GN ORFNames=ARALYDRAFT_479752 {ECO:0000313|EMBL:EFH59620.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- FUNCTION: Plant lipoxygenase may be involved in a number of diverse
CC aspects of plant physiology including growth and development, pest
CC resistance, and senescence or responses to wounding.
CC {ECO:0000256|RuleBase:RU003975}.
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962,
CC ECO:0000256|RuleBase:RU003974};
CC -!- PATHWAY: Lipid metabolism; oxylipin biosynthesis.
CC {ECO:0000256|RuleBase:RU003975}.
CC -!- SIMILARITY: Belongs to the lipoxygenase family.
CC {ECO:0000256|ARBA:ARBA00009419, ECO:0000256|RuleBase:RU003974}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR EMBL; GL348715; EFH59620.1; -; Genomic_DNA.
DR RefSeq; XP_002883361.1; XM_002883315.1.
DR AlphaFoldDB; D7L1P1; -.
DR STRING; 81972.D7L1P1; -.
DR EnsemblPlants; fgenesh2_kg.3__2453__AT3G22400.1; fgenesh2_kg.3__2453__AT3G22400.1; fgenesh2_kg.3__2453__AT3G22400.1.
DR Gramene; fgenesh2_kg.3__2453__AT3G22400.1; fgenesh2_kg.3__2453__AT3G22400.1; fgenesh2_kg.3__2453__AT3G22400.1.
DR eggNOG; ENOG502QQSP; Eukaryota.
DR HOGENOM; CLU_004282_0_0_1; -.
DR UniPathway; UPA00382; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:1990136; F:linoleate 9S-lipoxygenase activity; IEA:EnsemblPlants.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0010311; P:lateral root formation; IEA:EnsemblPlants.
DR GO; GO:0034440; P:lipid oxidation; IEA:EnsemblPlants.
DR GO; GO:1900366; P:negative regulation of defense response to insect; IEA:EnsemblPlants.
DR GO; GO:0031408; P:oxylipin biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd01751; PLAT_LH2; 1.
DR Gene3D; 3.10.450.60; -; 1.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR InterPro; IPR000907; LipOase.
DR InterPro; IPR013819; LipOase_C.
DR InterPro; IPR036226; LipOase_C_sf.
DR InterPro; IPR020834; LipOase_CS.
DR InterPro; IPR020833; LipOase_Fe_BS.
DR InterPro; IPR001246; LipOase_plant.
DR InterPro; IPR042057; Lipoxy_PLAT/LH2.
DR InterPro; IPR027433; Lipoxygenase_dom_3.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR PANTHER; PTHR11771:SF112; LINOLEATE 9S-LIPOXYGENASE 5; 1.
DR PANTHER; PTHR11771; LIPOXYGENASE; 1.
DR Pfam; PF00305; Lipoxygenase; 1.
DR Pfam; PF01477; PLAT; 1.
DR PRINTS; PR00087; LIPOXYGENASE.
DR PRINTS; PR00468; PLTLPOXGNASE.
DR SMART; SM00308; LH2; 1.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR SUPFAM; SSF48484; Lipoxigenase; 1.
DR PROSITE; PS00711; LIPOXYGENASE_1; 1.
DR PROSITE; PS00081; LIPOXYGENASE_2; 1.
DR PROSITE; PS51393; LIPOXYGENASE_3; 1.
DR PROSITE; PS50095; PLAT; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964, ECO:0000256|RuleBase:RU003974};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160,
KW ECO:0000256|RuleBase:RU003975};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU003974};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516,
KW ECO:0000256|RuleBase:RU003975};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU003974};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003974};
KW Oxylipin biosynthesis {ECO:0000256|ARBA:ARBA00022767,
KW ECO:0000256|RuleBase:RU003975};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694}.
FT DOMAIN 12..155
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 158..838
FT /note="Lipoxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51393"
FT REGION 206..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..241
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 838 AA; 95692 MW; 88C211C8200D7971 CRC64;
MEEDVKKTTM KIEGEVVVMK KNLLDFKDVM ASLLDRVHEL FGRRVSLHLI SSHQPDPANE
KRGRLGKAAH LEKWVTKLKT SVTAEETAFR VTFDWDESMG PPAAFVIKNH HHSQFYLKSL
TLRGFPGGEG GPIHFVCNSW IYPSHRYRSD RVFFSNKAYL PSETPELIKE LREEELQNLR
GNEKEGEFKE WDRVYDYAYY NDLGAPDKGP DSARPVLGGS PELPYPRRGK TGRKPTKSDP
KSESRLALLN LNIYVPRDER FSHVKFSDFL AYALKSVTQV LVPEIASMFF TSMTVVLSSP
NGHTISKLRD VIPWEMFREL VRNDGERFLN RSAWRTDEEF AREMLAGLNP VVISRLQEFP
PKSNLDSAKY GNQHSSIREE HIEPNMNGLN VLEALEQNKL YILDHHDALM PYLTRINSTN
TKTYATRTLL LLQEDGTLKP LAIELSLPHA QGESHGSVSK VFTPAEKGVE GSVWQLAKAY
AAVNDSGYHQ LISHWLQTHA VIEPFIIASN RQLSVVHPIH KLLHPHFRDT MNINALARHI
LINSDGVLER TVFPSRYAME MSSSIYKNWV FTDQALPKDL LKRGVAVEDP KSDNGVKLLI
DDYPFAVDGL EIWSAIKTWV TEYCTFYYKN DKTVQTDTEI QSWWTELRTK GHGDKQHESW
WPSMQTRDDL IETCTIIIWI ASALHAAVNF GQYPYAGFLP NRPTVSRRFM PEPGTDEYAE
LAEDADVAFL KTITPQLQTL LGISIIEILS MHSTDEIYLG QRDSPNWTAD DEPLEAFKRF
GKELELIENN IIRRNNDKRF KNRTGPVNIP YTLLYPNTSD YTREGGLTGK GIPNSVSI
//
