ID D7L5U9_ARALL Unreviewed; 360 AA.
AC D7L5U9;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Acyl-[acyl-carrier-protein] hydrolase {ECO:0000256|RuleBase:RU363096};
DE EC=3.1.2.- {ECO:0000256|RuleBase:RU363096};
GN Name=ATFATA {ECO:0000313|EMBL:EFH61940.1};
GN ORFNames=ARALYDRAFT_480016 {ECO:0000313|EMBL:EFH61940.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- FUNCTION: Plays an essential role in chain termination during de novo
CC fatty acid synthesis. {ECO:0000256|RuleBase:RU363096}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000256|ARBA:ARBA00004229, ECO:0000256|RuleBase:RU363096}.
CC -!- SIMILARITY: Belongs to the acyl-ACP thioesterase family.
CC {ECO:0000256|ARBA:ARBA00006500, ECO:0000256|RuleBase:RU363096}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL348715; EFH61940.1; -; Genomic_DNA.
DR RefSeq; XP_002885681.1; XM_002885635.1.
DR AlphaFoldDB; D7L5U9; -.
DR STRING; 81972.D7L5U9; -.
DR EnsemblPlants; fgenesh2_kg.3__2717__AT3G25110.1; fgenesh2_kg.3__2717__AT3G25110.1; fgenesh2_kg.3__2717__AT3G25110.1.
DR Gramene; fgenesh2_kg.3__2717__AT3G25110.1; fgenesh2_kg.3__2717__AT3G25110.1; fgenesh2_kg.3__2717__AT3G25110.1.
DR eggNOG; ENOG502QTE3; Eukaryota.
DR HOGENOM; CLU_045466_1_2_1; -.
DR OrthoDB; 1207631at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0016297; F:acyl-[acyl-carrier-protein] hydrolase activity; IEA:EnsemblPlants.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00586; 4HBT; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR InterPro; IPR049427; Acyl-ACP_TE_C.
DR InterPro; IPR002864; Acyl-ACP_thioesterase_NHD.
DR InterPro; IPR045023; FATA/B.
DR InterPro; IPR029069; HotDog_dom_sf.
DR PANTHER; PTHR31727; OLEOYL-ACYL CARRIER PROTEIN THIOESTERASE 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR31727:SF6; OLEOYL-ACYL CARRIER PROTEIN THIOESTERASE 1, CHLOROPLASTIC; 1.
DR Pfam; PF01643; Acyl-ACP_TE; 1.
DR Pfam; PF20791; Acyl-ACP_TE_C; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
PE 3: Inferred from homology;
KW Chloroplast {ECO:0000256|ARBA:ARBA00022528, ECO:0000256|RuleBase:RU363096};
KW Fatty acid biosynthesis {ECO:0000256|RuleBase:RU363096};
KW Fatty acid metabolism {ECO:0000256|RuleBase:RU363096};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU363096};
KW Lipid biosynthesis {ECO:0000256|RuleBase:RU363096};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098,
KW ECO:0000256|RuleBase:RU363096};
KW Plastid {ECO:0000256|ARBA:ARBA00022640, ECO:0000256|RuleBase:RU363096};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT DOMAIN 81..217
FT /note="Acyl-ACP thioesterase N-terminal hotdog"
FT /evidence="ECO:0000259|Pfam:PF01643"
FT DOMAIN 245..356
FT /note="Acyl-ACP thioesterase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20791"
SQ SEQUENCE 360 AA; 40773 MW; D3679D7871A0C07B CRC64;
MLKLSCNVTD SKLQRSLLFF SHSHRSDPVN FIRRRIVSCS QTKKTGLVPL RAVVSTDQGT
VIQGLGTLAD QLRLGSLTED GLSYKEKFVV RSYEVGSNKT ATIETIANLL QEVGCNHAQS
VGFSTDGFAT TPTMRKLHLI WVTARMHIEI YKYPAWGDVV EIETWCQSEG RIGTRRDWIL
KDCVTGEVTG RATSKWVMMN QDTRRLQKVS DDVRDEYLVF CPQELRLAFP EENNRSLKKI
PKLEDPAQYS MIGLKPRRAD LDMNQHVNNV TYIGWVLESI PQEIVDTHEL QVITLDYRRE
CQQDDVVDSL TTSEIGGTNG SATSGKQGHN DSQFLHLLRL SGDGQEINRG TTLWRKKPSR
//
