ID D7LEY1_ARALL Unreviewed; 958 AA.
AC D7LEY1;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=ARALYDRAFT_344999 {ECO:0000313|EMBL:EFH57483.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; GL348716; EFH57483.1; -; Genomic_DNA.
DR RefSeq; XP_002881224.1; XM_002881178.1.
DR AlphaFoldDB; D7LEY1; -.
DR STRING; 81972.D7LEY1; -.
DR EnsemblPlants; fgenesh1_pg.C_scaffold_4001341; fgenesh1_pg.C_scaffold_4001341; fgenesh1_pg.C_scaffold_4001341.
DR GeneID; 9317291; -.
DR Gramene; fgenesh1_pg.C_scaffold_4001341; fgenesh1_pg.C_scaffold_4001341; fgenesh1_pg.C_scaffold_4001341.
DR KEGG; aly:9317291; -.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_007358_0_1_1; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF458; GLUTAMATE RECEPTOR 3.5; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT TRANSMEM 611..629
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 671..697
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 853..877
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 490..832
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 930..958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 781..836
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 958 AA; 107189 MW; 24BAD7AD313BA33E CRC64;
MGFFVMIRVR DVSMGLMLLC VFALWVLPIQ GAGRESFSRN SSSSPLPSSV NVGALFTYDS
FIGRAAKLAF VVAIDDVNAD QSILRGTKLN IVFQDANCSG FVGTMGALQL MENRVVAAIG
PQSSGIGHII SHVANELHVP LLSFAATDPT LSSLQYPYFL RTTQNDYFQM NAIADFVSYF
RWREVVAIFV DDEYGRNGIS VLGDILAKKR AKISYKAAFT PGADSSSISD LLASVNLMES
RIFVVHVNPD SGLNIFSVAK SLGMMGSGYV WITSDWLLTA LDSIEPLDTK AMDLLQGVVA
FGHYTPESDN KKRFKARWKN LRSKESLKSD DGFNSYALYA YDSVWLVAHA LDVFFSQGNT
VTFSNDPNLR NTNDSNIKLS KLNIFNEGER FLQVMLEMNF TGLTGQIEFN SEKNRINPAY
DIVNIKSTGP QRVGYWSNHT GFSVVPPETL YSKPSNISAK NQRLNGIIWP GEVIKPPRGW
VFPDNGKPLK IGVPNRVSYK NYASKDNNPL GVKGYCIDIF EAAVQLLPYP VPRTYILYGD
GKKNPSYDNL ISEVAANSFD AAVGDVTIIT NRTKFVDFTQ PFIESGLVVV APVKGAKSSP
WSFLKPFTIE MWAVTGALFL FVGAVIWILE HRFNEEFRGP PRRQIITVFW FSFSTMFFSH
RENTVSTLGR FVLLVWLFVV LIINSSYTAS LTSILTVQQL TSRIEGMDTL IASNEPIGVQ
DGTFAWKYLV NELNIAPSRI IPLKDEEEYL SALQRGPRGG GVAAIVDELP YIKALLSNSN
CKFRTVGQEF TRTGWGFAFQ RDSPLAVDMS TAILQLAEDG KLEKIRKKWL TYDHECTMQI
SDTENYQISV QSFWGLFLIC GIVWFIALTL FCWKVFWQYQ RLRPEESDEV RARSEEAGSS
RGKSLRAVSF KDLIKVVDKR EAEIKEMLKE KSSKKLKAGQ SSGENSQSKD HETPRLDR
//
