ID D7M3T8_ARALL Unreviewed; 498 AA.
AC D7M3T8;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Integral membrane transporter family protein {ECO:0000313|EMBL:EFH48395.1};
DE Flags: Fragment;
GN ORFNames=ARALYDRAFT_489360 {ECO:0000313|EMBL:EFH48395.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC biopterin transporter (TC 2.A.71) family.
CC {ECO:0000256|ARBA:ARBA00007015}.
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DR EMBL; GL348718; EFH48395.1; -; Genomic_DNA.
DR RefSeq; XP_002872136.1; XM_002872090.1.
DR AlphaFoldDB; D7M3T8; -.
DR EnsemblPlants; fgenesh2_kg.6__2494__AT5G25050.1; fgenesh2_kg.6__2494__AT5G25050.1; fgenesh2_kg.6__2494__AT5G25050.1.
DR Gramene; fgenesh2_kg.6__2494__AT5G25050.1; fgenesh2_kg.6__2494__AT5G25050.1; fgenesh2_kg.6__2494__AT5G25050.1.
DR eggNOG; ENOG502QPUV; Eukaryota.
DR HOGENOM; CLU_018563_1_1_1; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd17484; MFS_FBT; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR039309; BT1.
DR InterPro; IPR004324; FBT.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; TIGR00788; fbt; 1.
DR PANTHER; PTHR31585; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR31585:SF6; FOLATE-BIOPTERIN TRANSPORTER 2-RELATED; 1.
DR Pfam; PF03092; BT1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 40..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFH48395.1"
SQ SEQUENCE 498 AA; 55360 MW; 09ACA63A17C778C9 CRC64;
VEEEQNLENG GSVHVVKGES NFRNVVCGPV RWLKMLSSEL HWSFVFGVVS LYGINQGLGG
SLGRVATEYY MKDVQKVQPS ESQALTAITK IPWIIKPLWG ILTDVLPIFG FHRRPYFILA
GVLGVVSLLF ISLHSNLHLY LALLWMTISS AAMAIADVTI DACTAYNSIK HPSLASDMQS
LCSLSSSIGA LLGFFMSGIL VHIVGSKVVF GLLTFPFALV SVVGIVFSEP HVPGFSYKQV
NQKFTDAGKA MWRTMKCSDV WRPSLYMYIS LTLGLNIHEG LFYWFTDSKD GPLFAQETVG
FILSIGSIGS ILGATLYQLV LKDHPFRGLC LWTQLLFALS GMLDLILVLR LNLKFGLPDY
LFIVVDEIVS QMIGRLKWMP LLVLTSKLCP HGIEGTFFAL LMSIDNAGLM TSSWLGGILL
HVLKVTRTEF HNLWLAVLVR NVMRLLPLCF LFLVPKGDQN TFKLPDEIMG EESEDSENEK
EGTRNLELAS LVQAVDRR
//
