ID D7M4G4_ARALL Unreviewed; 827 AA.
AC D7M4G4;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 22-FEB-2023, entry version 74.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFH49811.1};
GN ORFNames=ARALYDRAFT_488058 {ECO:0000313|EMBL:EFH49811.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
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DR EMBL; GL348718; EFH49811.1; -; Genomic_DNA.
DR RefSeq; XP_002873552.1; XM_002873506.1.
DR AlphaFoldDB; D7M4G4; -.
DR STRING; 81972.D7M4G4; -.
DR EnsemblPlants; fgenesh2_kg.6__1192__AT5G12150.1; fgenesh2_kg.6__1192__AT5G12150.1; fgenesh2_kg.6__1192__AT5G12150.1.
DR Gramene; fgenesh2_kg.6__1192__AT5G12150.1; fgenesh2_kg.6__1192__AT5G12150.1; fgenesh2_kg.6__1192__AT5G12150.1.
DR eggNOG; KOG4271; Eukaryota.
DR HOGENOM; CLU_011283_1_0_1; -.
DR OrthoDB; 5395569at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:EnsemblPlants.
DR GO; GO:0009574; C:preprophase band; IEA:EnsemblPlants.
DR GO; GO:0009920; P:cell plate formation involved in plant-type cell wall biogenesis; IEA:EnsemblPlants.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00821; PH; 1.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR025757; MIP1_Leuzipper.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR46265:SF8; RHO GTPASE-ACTIVATING PROTEIN 6; 1.
DR PANTHER; PTHR46265; RHO GTPASE-ACTIVATING PROTEIN 7; 1.
DR Pfam; PF14389; Lzipper-MIP1; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694}.
FT DOMAIN 18..125
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 172..371
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 379..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 566..625
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 649..683
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 783..810
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 391..415
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 827 AA; 91412 MW; 3CC4D2DCC3F5E3EA CRC64;
MEASLAAMQR PQAGALNTVY KSGPLFISSK GLGWTSWKKR WFILTRTSLV FFKNDPSALP
QKGGEVNLTL GGIDLNSSGS VVVREDKKLL TVLFPDGRDG RAFTLKAETL DDLYEWKAAL
EQALAQAPNA ALVIGQNGIF RTEANNTIEA SFNSWRDQRP LKSSVVGRPI LLALEEIDGS
PSFLEKALQF LETYGTKVEG ILRQSADVEE VERRVQEYEQ GKTEFSPEED PHVVGDCVKH
VLRQLPSSPV PASCCTALLE AYKIDHNEAR VNSLRSAIIE TFPEPNRRLL LRILKMMHTV
TSHSSENRMT SSAVAACMSP LLLRPLLAGE CDLEGFDSLG DNSAQLLAAA NAANNAQAIV
TALLEDYGNM INDKGLERCS TSTDSHIGDS GPENSSDEED IEVKHPDLHT LNIEEGETDD
DNDVLLSRKP SESSDYAGSD LYDYKGFGVE DSDAESPRDI HCSVESTDFP TRVKKHMEEP
IKDIEVSSVS PTENCYQSGR EAIPSVTPST PPTALKYTTS AEKPASKTTG SSTVNSKRSS
SWGRGNGKKT PAKGSFDSSG NDELLIQRLE HMKDELRQRI AKEAKGNAAL QASLERRKQA
LHERRLALEQ DVGRLQEQLQ AERDLRSALE VGLSISCGQF SSQAADSKTR AELEEIALAE
ADVARLKQKV AELHHQLNQQ RQHHLSSLPD AQSHHQFLHN HNTQLKSFQQ DFDSILAFVN
HERNQRTDET SLRADWRNGR GNNRQVPGSP SLNAASLGIP MEEFSPVMDY GRHHHPPAAS
AALMELTTRL DFFKERRSQL MEQIQNLDLN YGSSSSSLHR SSSPPWN
//
