ID D7MLN5_ARALL Unreviewed; 860 AA.
AC D7MLN5;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=ARALYDRAFT_494895 {ECO:0000313|EMBL:EFH40154.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; GL348720; EFH40154.1; -; Genomic_DNA.
DR RefSeq; XP_002863895.1; XM_002863849.1.
DR AlphaFoldDB; D7MLN5; -.
DR STRING; 81972.D7MLN5; -.
DR EnsemblPlants; fgenesh2_kg.8__711__AT5G48400.2; fgenesh2_kg.8__711__AT5G48400.2; fgenesh2_kg.8__711__AT5G48400.2.
DR GeneID; 9299971; -.
DR Gramene; fgenesh2_kg.8__711__AT5G48400.2; fgenesh2_kg.8__711__AT5G48400.2; fgenesh2_kg.8__711__AT5G48400.2.
DR KEGG; aly:9299971; -.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_007358_0_0_1; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 3.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF434; GLUTAMATE RECEPTOR 1.2-RELATED; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..860
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003103349"
FT TRANSMEM 558..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 618..638
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 787..808
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 438..767
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
SQ SEQUENCE 860 AA; 97065 MW; BEF0E97EF5D9B7A4 CRC64;
MERFCIQNSF LLVLLFFISN CFASSQNNDD DERIQVRVGL VLDLGSLEGK IVRSSVSMAL
SDFYAINNDY KTRVSLLVRD SHGEPLLGLA SVVDLLKTEG VEVIIGGNSL LEAKLLAELG
ERARVPVISL NSPMSLSLSK YTHLIQATHD SASEVKGITA FLHGFDWNSV ALVYEDDDDW
RESMHFMVDH FHENNVRVQS KVGFSVSSSE DSLMDRLRKL KDLGTTVFVV HLSEVLATRL
FPCAEKLGLM GEGFAWILTA KSMSSLHESI DDFAKEAMEG VVGFKSYIPM SKELHNFTLR
WRKSLHVEEV TGSEITRLSI SGVWAHDIAW ALASAAEVTR MPNVSSTLLE AISESRFKGL
SGDFQLHDKK LLSKKFEIVN MIGSGERRVG FWNSNGSFSN RRHLSSTHDK LETIIWPGGS
AQSPKGSSLR ESGRKKLRVL VTSSNRFPRL MKVETDPVTN AITIVEGFCI EVFQASIAPF
NYEVEYIRWL NGTNYTKLAY ALHSQKDKYD AAVGDITITS DRSTYADFTL PFTEMGLGIV
AAKERSMWVF FQPLTPNLWI TSAAFFVLTG IIVWLIERAE NKEFQGSWPQ QIGVVLWFGF
STLVYAHREK LKHNLSRFVV TVWVFAVLIL VTSYTATLTS MMTVQQIRFN ANEDYVGHLS
GSLIANAALT NSSLRTMRLL GLNTSEDYAQ ALLNKNVSYI VSELPYLKVL LGEYPGHFLM
VKTQSTTNGF GFMFQKGSEL VHNVSREIAK LRTSERLNEM ERRWFDKQLP YTTDDTSNPI
TLYRFRGLFM ITGVSFAFAL AVLLILWLRE KSEIVVKSVN LYLSQQLRHF RFLFTRTIHP
SPLDNPIGEN AVQMAQRNRR
//
