ID D7NE51_9BACT Unreviewed; 212 AA.
AC D7NE51;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Thymidylate synthase {ECO:0000313|EMBL:EFI48198.1};
GN ORFNames=HMPREF0665_01827 {ECO:0000313|EMBL:EFI48198.1};
OS Segatella oris C735.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Segatella.
OX NCBI_TaxID=563008 {ECO:0000313|EMBL:EFI48198.1, ECO:0000313|Proteomes:UP000003805};
RN [1] {ECO:0000313|EMBL:EFI48198.1, ECO:0000313|Proteomes:UP000003805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C735 {ECO:0000313|EMBL:EFI48198.1,
RC ECO:0000313|Proteomes:UP000003805};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Sibley C.D., Field T.R., Grinwis M., Eshaghurshan C.S., Surette M.G.,
RA Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Prevotella oris strain C735.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL349569; EFI48198.1; -; Genomic_DNA.
DR RefSeq; WP_004378117.1; NZ_GL349569.1.
DR AlphaFoldDB; D7NE51; -.
DR GeneID; 85011033; -.
DR eggNOG; COG0207; Bacteria.
DR HOGENOM; CLU_021669_0_0_10; -.
DR Proteomes; UP000003805; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.572.10; Thymidylate synthase/dCMP hydroxymethylase domain; 2.
DR InterPro; IPR045097; Thymidate_synth/dCMP_Mease.
DR InterPro; IPR023451; Thymidate_synth/dCMP_Mease_dom.
DR InterPro; IPR036926; Thymidate_synth/dCMP_Mease_sf.
DR PANTHER; PTHR11548; THYMIDYLATE SYNTHASE 1; 1.
DR PANTHER; PTHR11548:SF1; THYMIDYLATE SYNTHASE-RELATED; 1.
DR Pfam; PF00303; Thymidylat_synt; 1.
DR SUPFAM; SSF55831; Thymidylate synthase/dCMP hydroxymethylase; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000003805};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 3..201
FT /note="Thymidylate synthase/dCMP hydroxymethylase"
FT /evidence="ECO:0000259|Pfam:PF00303"
SQ SEQUENCE 212 AA; 24542 MW; 06A4D5CCBC21569B CRC64;
MNKYHEILKR IIVSGKTQHN RKGCIRYLLN EQLSLSPVDL LDIFESHGIA RKKLKNELQL
FMQGERQVQK YREVGINWWD YCGSVLVNSY PTYFEKLPPL IAKINREKRN SKNYVLFLGE
TGAESNQAPC LSLVQFQIDD GELVLSAYQR SSDANLGLPA DIYHLYLMAQ QIDLPLKNIT
LNLGNVHIYE NNLERTRLLL DGDETVRFEL NV
//
