ID D7P6M1_CULTA Unreviewed; 2119 AA.
AC D7P6M1;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Vitellogenin 1b {ECO:0000313|EMBL:ADH04225.1};
GN Name=Vg1b {ECO:0000313|EMBL:ADH04225.1};
OS Culex tarsalis (Encephalitis mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7177 {ECO:0000313|EMBL:ADH04225.1};
RN [1] {ECO:0000313|EMBL:ADH04225.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20465817; DOI=10.1186/1471-2148-10-142;
RA Chen S., Armistead J.S., Provost-Javier K.N., Sakamoto J.M., Rasgon J.L.;
RT "Duplication, concerted evolution and purifying selection drive the
RT evolution of mosquito vitellogenin genes.";
RL BMC Evol. Biol. 10:142-142(2010).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00557}.
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DR EMBL; GU017910; ADH04225.1; -; Genomic_DNA.
DR GO; GO:0005319; F:lipid transporter activity; IEA:InterPro.
DR GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR Gene3D; 2.20.80.10; Lipovitellin-phosvitin complex, chain A, domain 4; 1.
DR Gene3D; 1.25.10.20; Vitellinogen, superhelical; 1.
DR InterPro; IPR015819; Lipid_transp_b-sht_shell.
DR InterPro; IPR011030; Lipovitellin_superhlx_dom.
DR InterPro; IPR015816; Vitellinogen_b-sht_N.
DR InterPro; IPR015255; Vitellinogen_open_b-sht.
DR InterPro; IPR001747; Vitellogenin_N.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR23345:SF37; APOLIPOPROTEIN LIPID TRANSFER PARTICLE; 1.
DR PANTHER; PTHR23345; VITELLOGENIN-RELATED; 1.
DR Pfam; PF09172; Vit_open_b-sht; 1.
DR Pfam; PF01347; Vitellogenin_N; 1.
DR Pfam; PF00094; VWD; 1.
DR SMART; SM01169; DUF1943; 1.
DR SMART; SM00638; LPD_N; 1.
DR SMART; SM00216; VWD; 1.
DR SUPFAM; SSF48431; Lipovitellin-phosvitin complex, superhelical domain; 1.
DR PROSITE; PS51211; VITELLOGENIN; 1.
DR PROSITE; PS51233; VWFD; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..2119
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003105312"
FT DOMAIN 41..962
FT /note="Vitellogenin"
FT /evidence="ECO:0000259|PROSITE:PS51211"
FT DOMAIN 1700..1914
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT REGION 354..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1960..2019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..416
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..453
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1960..1999
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2000..2019
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2119 AA; 242369 MW; DA7270693A5F7FCE CRC64;
MFAKLLLLAL VGISAAYQYE YQNEFYNQRP ENKTGFEFGA WEPNREYVYN VTSRTMTALA
DLADQWTGVI TRARLIVRPK DPDYVVCYVK QAEYANFNEE LPQGYRTNIW RELGSKLKWQ
PMPFSSKPFA IRYRKGAIKG LYVEQTVPNH EVNILKAWAS QLQLDTRGAN VVKSKYNQFP
ENTTFTGVYK VMEPLVTGEC ETLYDVNVVP EHVIKGNKYF VPRPDLREEN QYFVEVHKTQ
NFNRCEQRMG YHFGFSGHSD FKPNSNQMGN VASKAVVGHM FLTGTWYNYT IQSSSTTNKV
VVAPSLVDDQ KAMVYSQVNM TLDKVTPYEK IPMGPAEDRQ VFVDLVYSYN MANDKKNSVR
PGNETDSSSS SSSSSSSSSS SSSSSSSSSS ESDSSSSSDS SSSSSEEQNN QKDNFKISPA
EQHKKQLKEV KARRTRRDLN AQKEKKYYEA YKMDQYRLSR NNDTSSDSSS SDDSKSSSSS
SSSSESNEKN ARISRFTNSP SSSSSSSSSS SSSSQSDSSS SSSESNSLSS EELYYQPMPE
SFKDAPQAPF LPFYTGYKGY TVQYARNVDG PRAVSKLVQE IADELQNPSS LPQSNTLNKF
NILCRAIRTM DYKEIYEVAQ KYFVSQKERK EGDNNSEEFS KRVDAWNTFR DALAEAGTPP
AFKVIKEFIE EKKLRGAEAA SVIATLPQSI RYPTEPLMHE FFLLVTSDTV QHQDSLNVTA
LISFTQFVNQ AQVNNRSAYN YYPVHSFGRL ADADYKIVAH KVVPWLAHQL REAVNEGDSI
KVQVYIRALG NLGHPEILNV FEPYLEGKIP VSDFQRLCIV AGMDKLVENF PKLARSVLFK
VFQNTGDVHE VRCAAVHLLI RAEPPVEMMQ RMAQQTNEEP SLYVRAAVKT ALEYAAQADE
YEADSSFANN AKAAIKLLDP EVYGLQYSSN YLRDVALNNL EMAFRMYVGQ IASDDHWLPN
GMIWHLRKNL GGVKRHTTFW YLVSSMETFL DLVDKQYDSS SISEDYKSAD YYYKYYQQFP
DKKSEYFEKY YKAHESQNEM NKKYNEQNGG KYFQKYSTTR IAKLLNIDPQ EAEELEGQLF
FPLFNGKYFA AFNNQTIENI PRKLKELADD LEDGMSFNVT KFYQYQPLTL AFPLASGLPF
VYTLKNPTVV KFETEATTKT HPSIVKKPAG HPETENDDFI HVPRVLNGSV NVNLVFHRLI
DSKIGFITPF DHQRYISGVQ KKVQAFLPLS LELNWDLEND QYETELEILD KKEDKLLFHL
SAWPYTGFKD ITDMRPIAEN PNAKIIHANE HNTQTFQQTV GQDMFGFALR VHAKYDQDII
DVQSILEHVQ EGDYLAALFH PFAYQPLYYH QLNVYYDAQR TGAKKARFSA HYNEGDFDQD
FQESDIKQPK GRHSYAGYFN ENNLAQPFVF TAGSQRRQEQ FIKNAAAGIR NSDVAVFDFG
FVFEGRERKA EYVLTTAYAD SPVDEKSRML FFFSGSPFNP SERFFGVPHN GKQFQMCFSA
TNEFPNMPKL NFLNALNHDM DSALRWELSY GEKCQGGAQV SMKGKLKQSD EYRHKLRISE
VGQRCKQQMD QGRFQLPECQ NATRQAGYLD QYKFEVDFKD VGSWAKNWTH KAVDWVQHMT
YPWFEPNYLF KGKNNKVEFE FEMSPYGDYF NVSAWAPEYA LEIENYPVDS FRARYFAAAH
TDLAWYERLG TYAYQGNYKS SCAVSSKYVD TFDGRNYQYN MGECWHVVLH TVKPDYEYYA
QQSHFQNADT EYRFKNGFSE DEQISVLARS GPSQELYFKV VLGQYKQNDY NIDVLPKGAE
LPEVFINGKP QQIHEKYAVE LYTNDNGGDQ PLFRCYALPG KELEISIRDD DVKIVFDGQR
ARIFADQKYF DNFVGLCGTN NGELYDDFVT PDQCFMSKPE FFAASYALTG QNCSGPAKAF
NVFYQQKVKE ECVKEEVFYG NVISEQEAGR KRYRYYNHNV EDSSSSSDSS DSSSSSSSSS
SSSESDSSSD SSSNSSSSSS EEEKRTRDIN KESKDTYKEF HADRQKHTLK ECEIQHQHQI
VEQGDKTCIT KRPLPVCPSH CVASNKLQKY VDVHCNNSDD QSVKLYKNQI SKGYNPDMSS
HPVTKTIKFN IPKTCVFAQ
//
