ID   D7PRP0_HELPX            Unreviewed;       440 AA.
AC   D7PRP0;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Truncated DupA {ECO:0000313|EMBL:ADI46656.1};
GN   Name=dupA {ECO:0000313|EMBL:ADI46656.1};
OS   Helicobacter pylori (Campylobacter pylori).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=210 {ECO:0000313|EMBL:ADI46656.1};
RN   [1] {ECO:0000313|EMBL:ADI46656.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=9367 {ECO:0000313|EMBL:ADI46656.1};
RX   PubMed=20533870; DOI=10.1086/653587;
RA   Hussein N.R., Argent R.H., Marx C.K., Patel S.R., Robinson K.,
RA   Atherton J.C.;
RT   "Helicobacter pylori dupA is polymorphic, and its active form induces
RT   proinflammatory cytokine secretion by mononuclear cells.";
RL   J. Infect. Dis. 202:261-269(2010).
CC   -!- SIMILARITY: Belongs to the TrbE/VirB4 family.
CC       {ECO:0000256|ARBA:ARBA00006512}.
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DR   EMBL; GU932725; ADI46656.1; -; Genomic_DNA.
DR   AlphaFoldDB; D7PRP0; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR018145; CagE_TrbE_VirB_cntrl_dom.
DR   InterPro; IPR002543; FtsK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF03135; CagE_TrbE_VirB; 1.
DR   Pfam; PF01580; FtsK_SpoIIIE; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          5..201
FT                   /note="CagE TrbE VirB component of type IV transporter
FT                   system central"
FT                   /evidence="ECO:0000259|Pfam:PF03135"
FT   DOMAIN          224..296
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|Pfam:PF01580"
SQ   SEQUENCE   440 AA;  50909 MW;  35C027C3261EAFEC CRC64;
     MSSVLTDFEP KFLSSDDLLN LYAEYCNGHY CDFKYKQGRL SDGNIQSHLY FKKDHFIHDF
     NGIETFKRFI AVKAYDVDNI TSLALSNLLC EKFNLDIFLT IETMDKERAL FFIRERKKRS
     KNISYQNIEY LEQMVSTDRA QIQKVSLSIM VFANSKKELD KKSIIVYNTL KKEGFSAVLE
     SINMRPIFFS FFPERNFLNS RLRPQTSQNI ASLIMFEKYQ EGFKENSWGN CPVSVFKNQN
     GSAHFFNFQA KQGKDKNDNV VGHTMIIGST GSGKSTFISF LIANLLTKYD MSVVALDRMN
     GLEIMTDFFE GQYNTANTDG GFYINPFSLK DTEENRQFLA NWIKFMLNIN SDNQQDNKAS
     QSIDKVIRDT YNYMGEQKNQ INLLEIAKNL GSSEQDFNEI LKSQGEKIYF KNFQDCLDFS
     KSPLSVINMD AFANDKNLWG
//